Pulse monitoring method, apparatus and device, and storage medium
A pulse monitoring method includes: applying a first pulse sequence and a second pulse sequence to target biological tissue; where a voltage of the second pulse sequence is smaller than a voltage of the first pulse sequence, and the first pulse sequence is used to ablate the target biological tissue; obtaining a feedback signal after the second pulse sequence is applied to the target biological tissue; determining, according to the feedback signal, whether a termination condition for the first pulse sequence is met; stopping applying the first pulse sequence when it is determined that the termination condition for the first pulse sequence is met.
1 . A pulse monitoring device, comprising: a pulse generating circuit, a control unit, a monitoring unit and a display unit; wherein,
the control unit is communicatively connected to the pulse generating circuit, and configured to control the pulse generating circuit to apply a first pulse sequence and a second pulse sequence to target biological tissue sequentially and alternately in a plurality of periods; wherein the second pulse sequence is applied in each period; a voltage of the second pulse sequence is smaller than a voltage of the first pulse sequence, and the first pulse sequence is used to ablate the target biological tissue;
the control unit is further configured to determine, according to a feedback signal forwarded by the monitoring unit, whether a termination condition for the first pulse sequence is met, and output a termination instruction for the first pulse sequence to the pulse generating circuit when it is determined that the termination condition for the first pulse sequence is met; and
the monitoring unit is communicatively connected to the control unit, and configured to obtain the feedback signal after the second pulse sequence is applied to the target biological tissue, and output the feedback signal to the control unit;
the pulse generating circuit is configured to stop applying the first pulse sequence when it is determined that the termination condition for the first pulse sequence is met;
the monitoring unit is further configured to obtain a real-time voltage and a real-time current of a feedback circuit corresponding to the target biological tissue after the second pulse sequence is applied to the target biological tissue;
the control unit is further configured to:
determine, according to the real-time voltage and real-time current of the feedback circuit, a real-time impedance value of the target biological tissue; and
determine whether the real-time impedance value is less than a set impedance value; or, display through the display unit the real-time impedance value and determine whether the termination instruction for the first pulse sequence is received; and
the control unit is further configured to:
stop applying the first pulse sequence when it is determined that the real-time impedance value is less than the set impedance value; or, stop applying the first pulse sequence when it is determined that the termination instruction for the first pulse sequence is received;
the pulse generating circuit comprises a first pulse generating circuit for outputting the first pulse sequence and a second pulse generating circuit for outputting the second pulse sequence;
the first pulse generating circuit and the second pulse generating circuit are integrated on a same circuit board;
the first pulse generating circuit comprises at least one level of first pulse generating units electrically connected sequentially;
each first pulse generating unit is electrically connected to the control unit, and configured to be turned on under control of the control unit and apply the first pulse sequence to the target biological tissue;
each of the at least one level of first pulse generating units comprises a first capacitor, a first switching device and a first diode, a first terminal of the first capacitor is electrically connected to a first terminal of the first switching device, a positive electrode and a negative electrode of the first diode are electrically connected to a second terminal of the first capacitor and a second terminal of the first switching device respectively, and a control terminal of the first switching device is electrically connected to the control unit.
2 . The pulse monitoring device according to claim 1 , wherein the first pulse generating circuit further comprises at least one second diode; a first terminal of a first capacitor in a first level of first pulse generating unit in the at least one level of first pulse generating units is electrically connected to a first power source through the at least one second diode.
3 . The pulse monitoring device according to claim 1 , wherein the first pulse generating circuit further comprises at least one third diode, an anode and a cathode of the third diode are electrically connected to two adjacent first pulse generating units respectively.
4 . The pulse monitoring device according to claim 1 , wherein the second pulse generating circuit comprises at least one level of second pulse generating units electrically connected sequentially;
wherein each second pulse generating unit is electrically connected to the control unit and configured to be turned on under control of the control unit and apply the second pulse sequence to the target biological tissue.
5 . The pulse monitoring device according to claim 4 , wherein the second pulse generating unit comprises a second capacitor, a second switching device and a fourth diode; a first terminal of the second capacitor is electrically connected to a first terminal of the second switching device, a positive electrode and a negative electrode of the fourth diode are electrically connected to a second terminal of the second capacitor and a second terminal of the second switching device respectively, and a control terminal of the second switching device is electrically connected to the control unit.
6 . The pulse monitoring device according to claim 1 , wherein the pulse monitoring device further comprises a display unit communicatively connected to the control unit, wherein the display unit is configured to display at least one of a real-time impedance value, a real-time impedance value curve or biological indicator information.
7 . The pulse monitoring device according to claim 1 , wherein the pulse monitoring device further comprises an alarm unit communicatively connected to the control unit, wherein the alarm unit is configured to issue an alarm prompt when the biological indicator information of the target biological tissue is greater than a set threshold.
8 . The pulse monitoring device according to claim 1 , wherein the pulse generating circuit is configured to apply a first set quantity of first pulse sequences and a second set quantity of second pulse sequences to the target biological tissue sequentially and alternately.
9 . The pulse monitoring device according to claim 1 , wherein the first pulse sequence comprises at least one type of pulse and the second pulse sequence comprises at least one type of pulse.
10 . The pulse monitoring device according to claim 1 , wherein the first pulse sequence comprises a nanosecond pulse, or the first pulse sequence comprises a nanosecond pulse and a microsecond pulse;
the second pulse sequence comprises a microsecond pulse.
11 . The pulse monitoring device according to claim 10 , wherein the voltage of the first pulse sequence is greater than 500 V and not greater than 15 kV.
12 . The pulse monitoring device according to claim 10 , wherein the voltage of the second pulse sequence is not greater than 500 V.
13 . The pulse monitoring device according to claim 1 , wherein the display unit is further configured to perform at least one of the following:
displaying a real-time impedance value curve, wherein the real-time impedance value curve comprises at least two real-time impedance values in a set time period; or,
displaying the real-time impedance value and corresponding biological indicator information of the target biological tissue; wherein the biological indicator information comprises at least one of the following: heart rate, blood pressure or blood oxygen concentration.
14 . The pulse monitoring device according to claim 1 , further comprising an alarm unit communicatively connected to the control unit, wherein the alarm unit is configured to issue an alarm prompt when the biological indicator information of the target biological tissue is greater than a set threshold; the alarm prompt comprises at least one of the following: emitting an alarm sound or outputting alarm information;
the control unit is further configured to output the termination instruction for the first pulse sequence in response to receiving the alarm information.