IP Library Granted Patent US 12697339
Granted Patent B2
US 12697339 · App. 18/299,416 · Granted Aug 4, 2026

Composition and methods of treatment using synergistically-enhanced supplementation

Inventor: Alexy Goldstein (LaFayette, CA)
Assignee: XYGENYX INC.
A61K31/52A61K9/0053A61K31/20A61K31/201A61K31/205
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 12697339
App. No.
18/299,416
Granted
Aug 4, 2026
Kind
B2
Abstract

A method and compositions of treatment for improving metabolic performance using supplementation, comprising the step of applying a supplement formulation to a human subject via a selected administration route, the supplement formulation comprising therapeutically effective amounts of a plurality of medium-chain triglycerides, a plurality of amino acids, and zeatin. The plurality of medium-chain triglycerides may comprise caprylic acid, and the plurality of amino acids may comprise carnitine which may be provided in the form of L-carnitine fumarate.

Claims (45)

1 . A method of treatment for improving metabolic performance using supplementation, comprising the step of:

applying a supplement formulation to a human subject via a selected administration route, the supplement formulation comprising therapeutically-effective amounts of:

a plurality of medium-chain triglycerides;

a plurality of amino acids; and

zeatin.

2 . The method of claim 1 , wherein the plurality of medium-chain triglycerides includes caprylic acid.

3 . The method of claim 1 , wherein the plurality of amino acids includes carnitine.

4 . The method of claim 3 , wherein the carnitine is provided in the form of L-carnitine fumarate.

5 . The method of claim 1 , wherein the plurality of amino acids includes a plurality of cetylated amino acids.

6 . The method of claim 5 , wherein the plurality of cetylated amino acids includes cetyl myristoleate.

7 . The method of claim 5 , wherein the plurality of cetylated amino acids includes cetylated alpha-linoleic acid.

8 . The method of claim 1 , wherein the therapeutically-effective amount of the plurality of medium-chain triglycerides is between 0.1 and 2 grams.

9 . The method of claim 1 , wherein the therapeutically-effective amount of the plurality of amino acids is between 0.1 and 1 grams.

10 . The method of claim 1 , wherein the therapeutically-effective amount of the zeatin is between 0.1 and 1 milligram per kilogram bodyweight of the human subject.

11 . The method of claim 1 , wherein the selected administration route comprises oral administration.

12 . The method of claim 1 , wherein the selected administration route comprises transdermal administration.

13 . The method of claim 9 , wherein the supplement formulation comprises an aqueous gel.

14 . A composition for oral supplementation, comprising:

an ingestible pill comprising, or capsule containing, therapeutically effective amounts of:

a plurality of medium-chain triglycerides;

a plurality of amino acids; and

zeatin.

15 . The composition of claim 14 , wherein the plurality of medium-chain triglycerides includes caprylic acid.

16 . The composition of claim 14 , wherein the plurality of amino acids includes carnitine.

17 . The composition of claim 16 , wherein the carnitine is provided in the form of L-carnitine fumarate.

18 . The composition of claim 14 , wherein the plurality of amino acids includes a plurality of cetylated amino acids.

19 . The composition of claim 18 , wherein the plurality of cetylated amino acids includes cetyl myristoleate.

20 . The composition of claim 18 , wherein the plurality of cetylated amino acids includes cetylated alpha-linoleic acid.

21 . The composition of claim 14 , wherein the therapeutically-effective amount of the plurality of medium-chain triglycerides is between 0.1 and 2 grams.

22 . The composition of claim 14 , wherein the therapeutically-effective amount of the plurality of amino acids is between 0.1 and 1 grams.

23 . The composition of claim 14 , wherein the therapeutically-effective amount of the plurality of zeatin is between 0.1 and 1 milligram per kilogram bodyweight of the human subject.

24 . A composition for transdermal supplementation, comprising:

an aqueous gel comprising therapeutically effective amounts of:

a plurality of medium-chain triglycerides;

a plurality of amino acids; and

zeatin.

25 . The composition of claim 24 , wherein the plurality of medium-chain triglycerides includes caprylic acid.

26 . The composition of claim 24 , wherein the plurality of amino acids includes carnitine.

27 . The composition of claim 26 , wherein the carnitine is provided in the form of L-carnitine fumarate.

28 . The composition of claim 24 , wherein the plurality of amino acids comprises a plurality of cetylated amino acids.

29 . The composition of claim 28 , wherein the plurality of cetylated amino acids includes cetyl myristoleate.

30 . The composition of claim 28 , wherein the plurality of cetylated amino acids includes cetylated alpha-linoleic acid.

31 . The composition of claim 24 , wherein the therapeutically-effective amount of the plurality of medium-chain triglycerides is between 0.1 and 2 grams.

32 . The composition of claim 24 , wherein the therapeutically-effective amount of the plurality of amino acids is between 0.1 and 1 grams.

33 . The composition of claim 24 , wherein the therapeutically-effective amount of the zeatin is between 0.1 and 1 milligram per kilogram bodyweight of the human subject.