Composition for the prevention and treatment of dysbiosis
The present invention refers to a composition for use in the prevention and/or treatment of dysbiosis. It also refers to the use of said composition for preparing a medicament for the prevention and/or treatment of dysbiosis. Furthermore, it refers to a method of preventing and/or treating of dysbiosis in which said composition is administered to a subject in need thereof.
1 . A method of treating dysbiosis in a human in need thereof comprising administering topically a therapeutic effective amount of a composition comprising an olive oil and/or olive fruit extract, betaine, and xylitol to said human, wherein the composition comprises 0.05%-5.1% by weight of the olive oil and/or olive fruit extract, 0.1%-10% by weight of betaine, and 1%-25% by weight of xylitol.
2 . The method of claim 1 , wherein the dysbiosis is mucosa dysbiosis or skin dysbiosis.
3 . The method of claim 2 , wherein the mucosa dysbiosis is oral dysbiosis.
4 . The method of claim 2 , wherein the dysbiosis is skin dysbiosis.
5 . The method of claim 2 , wherein the mucosa dysbiosis is vagina dysbiosis.
6 . The method of claim 2 , wherein the mucosa dysbiosis is lung dysbiosis.
7 . The method of claim 3 , wherein the oral dysbiosis is selected from the group consisting of halitosis dysbiosis, caries dysbiosis, periodontal dysbiosis, aphthous dysbiosis, periimplantitis dysbiosis, Lichen Planus dysbiosis, Pemphigus dysbiosis, sleep apnea dysbiosis, stress dysbiosis, tooth wear dysbiosis, diabetes oral dysbiosis, cancer oral dysbiosis, and combinations thereof.
8 . The method of claim 4 , wherein the skin dysbiosis is selected from the group consisting of atopic dermatitis dysbiosis, acne vulgaris dysbiosis, psoriasis dysbiosis, xeroderma dysbiosis, skin allergies dysbiosis, radiodermatitis dysbiosis, solar dermatitis dysbiosis, contact dermatitis dysbiosis, seborrheic dermatitis dysbiosis, scalp dysbiosis, body malodor dysbiosis, premature skin aging dysbiosis, Lichen Planus dysbiosis, Pemphigus dysbiosis, and combinations thereof.
9 . The method of claim 6 , wherein the lung dysbiosis is selected from the group consisting of chronic pulmonary dysbiosis, chronic obstructive pulmonary dysbiosis, cystic fibrosis dysbiosis, asthma dysbiosis, tracheitis dysbiosis, bronchitis dysbiosis, infectious respiratory dysbiosis.
10 . The method of claim 1 , wherein the olive fruit extract is olive fruit dry extract and/or olive fruit liquid extract; and/or
wherein the olive fruit extract comprises at least 20% w/w of hydroxytyrosol; and/or
wherein the olive oil is extra virgin olive oil, virgin olive oil, or a combination thereof;
and/or
wherein betaine is selected from the group consisting of trimethylglycine, cocamidopropyl betaine, dimethylamine betaine, alkyl (C 12 -C 18 ) amido betaines, alkyl (C 8 -C 18 ) betaines, amidobetaines, alkyl amido betaines, sulpho hydroxy betaines and combinations thereof.
11 . The method of claim 1 , wherein the composition comprises 0.05%-2.6% by weight of the olive oil and/or olive fruit extract.
12 . The method of claim 1 , wherein the composition comprises 1.0%-6% by weight of betaine.
13 . The method of claim 1 , wherein the composition comprises 1%-20% by weight of xylitol.
14 . The method of claim 1 , wherein the composition comprises 0.05%-5.1% by weight of the olive oil and/or olive fruit extract, 0.1%-10% by weight of betaine, and 1%-20% by weight of xylitol.
15 . The method of claim 1 , wherein the composition additionally comprises one or more antioxidants, vitamins, prebiotics, and/or probiotics.
16 . The method of claim 1 , wherein the composition comprises the olive oil and/or olive fruit extract, betaine and xylitol as the only active ingredients.