IP Library Granted Patent US 12697402
Granted Patent B2
US 12697402 · App. 17/432,070 · Granted Aug 4, 2026

Detection of colonic neoplasia in vivo using near-infrared peptide targeted against overexpressed cMet

Inventors: Thomas D. Wang (Ann Arbor, MI); Juan Zhou (Ann Arbor, MI)
Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
A61K49/0056A61K49/0032A61K49/0043C07K7/06
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Quick Facts
Patent No.
US 12697402
App. No.
17/432,070
Granted
Aug 4, 2026
Kind
B2
Abstract

The disclosure provides peptides, including labeled peptides, that selectively bind to the cMet protein. The disclosure also provides methods of detecting dysplastic cells and tissue, e.g., in the colon, providing early identification of precancerous and cancerous tissue.

Claims (1)

1 . A peptide consisting of the amino acid sequence QQTNWSL set forth in SEQ ID NO:1.