IP Library › Granted Patent US 12698283
Granted Patent B2
US 12698283 · App. 18/003,758 · Granted Aug 4, 2026

Quinoline derivatives, pharmaceutically acceptable salts, and methods of use thereof

Inventor: Bapu Gaddam (Ellicott City, MD)
Assignee: vTv Therapeutics LLC
C07D471/04
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Quick Facts
Patent No.
US 12698283
App. No.
18/003,758
Granted
Aug 4, 2026
Kind
B2
Abstract

The present disclosure relates to the compound trans-4-[1-(3-chlorophenyl)-7-methoxy-2,4-dioxo-pyrimido[5,4-c]quinolin-3-yl]cyclohexanecarboxylic acid, pharmaceutically acceptable salts, and use thereof as a therapeutic agent including treatment of inflammatory disorders.

Claims (6)

1 . A compound having the Formula (I):

or a pharmaceutically acceptable salt thereof.

2 . The compound of claim 1 , wherein the compound is a compound of Formula (I).

3 . The compound of claim 1 , wherein the compound is an acid salt of the compound of Formula (I).

4 . The compound of claim 3 , wherein the compound is an HCl salt of the compound of Formula (I).

5 . A pharmaceutical composition comprising a compound of claim 1 , or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable carrier.