Photonic integrated chip for spectroscopy

1 . An optical sensor for a spectroscopic analysis of a sample, the optical sensor comprising:

a photonic integrated chip (PIC) for providing light to the sample, the PIC comprising:

one or more laser(s) disposed on the PIC and configured to operate to output laser light at one or more respective predetermined wavelength(s), each of the one or more laser(s) having an output that is optically coupled to an optical output of the PIC;

a monitor disposed on the PIC and comprising a wavemeter disposed on the PIC and providing output to a photodiode likewise disposed on the PIC, the monitor configured to determine the wavelength of the optical output of each of the one or more laser(s); and

a detector disposed on the PIC and configured to collect a spectrum from the sample; and

one or more processors configured to:

compare the wavelength of the laser(s) at the optical output with each of their respective predetermined wavelength(s); and

in accordance with a determination that a deviation above a threshold is detected between the wavelength of the laser(s) and the predetermined wavelength(s), adapt the collected spectrum to generate a reconstructed spectrum; and

use one or more datapoints from the reconstructed spectrum for the spectroscopic analysis.

2 . The optical sensor of claim 1 , wherein the spectroscopic analysis includes application of an algorithm, one or more input values of the algorithm corresponding to datapoints corresponding to one or more of the predetermined wavelength(s).

3 . The optical sensor of claim 1 wherein at least one of the one or more lasers is optically coupled to the wavelength monitor in addition to being optically coupled to the optical output of the PIC.

4 . The optical sensor of claim 1 wherein the monitor comprises a temperature sensor configured to record the temperature of the PIC, which is then converted to a wavelength value via a predetermined calibration coefficient.

5 . The optical sensor of claim 1 wherein the reconstructed spectrum is achieved via interpolation and/or extrapolation of values taken during a calibration stage.

6 . The optical sensor of claim 5 , wherein the interpolation is linear or spline interpolation.

7 . The optical sensor of claim 1 , wherein the one or more lasers is a plurality of lasers, and wherein a single wavelength monitor is shared by the plurality of lasers.

8 . The optical sensor of claim 1 , further comprising one or more additional wavelength monitors; wherein the plurality of lasers are split into sub-groups; each sub-group of lasers being optically coupled to a respective wavelength monitor.

9 . The optical sensor according to claim 1 wherein the calibration stage includes one or more of: characterizing laser wavelengths emitted from the PIC, calibrating laser wavelength(s) emitted from the PIC as a function of drive conditions or external conditions; calibration of on-PIC sensor(s); calibration of a wavemeter as a function of external conditions; and/or storing one or more predetermined wavelength(s).

10 . The optical sensor according to claim 1 , wherein the predetermined laser wavelength(s) is/are aligned at quadrature points of the wavelength monitor.

11 . A optical sensor according to claim 1 wherein the PIC and the detector are located on a wearable device.

12 . The optical sensor of claim 1 , wherein the PIC further comprises one or more sensor(s) for measuring a condition of the PIC.

13 . The optical sensor of claim 12 , wherein the condition is one or more of: temperature, and laser drive current.

14 . The optical sensor of claim 1 wherein the wavelength monitor comprises a wavemeter and a photodiode, wherein a drift in wavelength of light entering the wavemeter over time generates a drift in photocurrent measured by the photodiode over time.

15 . The optical sensor of claim 14 , wherein the wavemeter comprises a Mach Zehnder interferometer (MZI).

16 . The optical sensor of claim 1 wherein the optical coupling of the wavelength monitor to the respective output(s) of the one or more laser(s) takes the form of an optical tap, which taps less than 5% of the light from the one or more laser(s).

17 . The optical sensor of claim 1 , wherein the plurality of lasers are fixed wavelength lasers.

18 . A method of spectroscopy, the method comprising:

providing the optical sensor according to claim 1 ;

collecting a spectrum at the detector;

adapting the collected spectrum to generate a reconstructed spectrum, in response to a measurement made by the monitor; and

performing analysis on the reconstructed spectrum to obtain information about one or more biomarkers at the optical sample.