Slit lamp microscope, ophthalmic information processing apparatus, ophthalmic system, method of controlling slit lamp microscope, and recording medium

1 . A slit lamp microscope comprising:

a scanner configured to scan a crystalline lens including opaque areas of an anterior segment of a subject's eye with slit light to collect a plurality of cross sectional images;

a reconstruction processor configured to apply three dimensional reconstruction to the plurality of cross sectional images collected by the scanner;

a segmentation processor configured to apply segmentation to a three dimensional reconstructed image constructed by the reconstruction processor to identify a crystalline lens region corresponding to at least part of the crystalline lens from the three dimensional reconstructed image;

a rendering processor configured to apply rendering to the crystalline lens region in which the opaque areas are depicted; and

a controller, wherein

the scanner includes

an illumination system configured to project the slit light onto at least the crystalline lens,

a photography system configured to perform photography of at least the crystalline lens from a direction different from the illumination system, and

a movement mechanism configured to move the illumination system and the photography system,

the controller is configured to control the illumination system to perform adjustment of intensity of the slit light,

wherein the photography system includes an optical system configured to direct light coming from the anterior segment onto which the slit light is projected, and an image sensor including a light detecting plane configured to receive the light directed by the optical system,

wherein a subject plane along an optical axis of the illumination system, the optical system, and the light detecting plane satisfy a Scheimpflug condition, and

the scanner is configured to scan the crystalline lens in a state in which focus of the photography system is on an entirety of at least an area from a cornea of the anterior segment to the crystalline lens by adjusting relative positions of the illumination system and the photography system using the movement mechanism.

2 . The slit lamp microscope of claim 1 , wherein the rendering processor is configured to apply projection onto a predetermined plane to the crystalline lens region.

3 . The slit lamp microscope of claim 2 , wherein the predetermined plane is perpendicular to a depth direction of the subject's eye.

4 . The slit lamp microscope of claim 1 , wherein

the segmentation processor is configured to apply segmentation to the crystalline lens region to identify a partial region that has a dimension in a depth direction of the subject's eye, and

the rendering processor is configured to apply the rendering to the partial region.

5 . The slit lamp microscope of claim 4 , wherein the segmentation processor is configured to identify at least one region of a capsule region and a nucleus region from the crystalline lens region, and identify the partial region based on the at least one region.

6 . The slit lamp microscope of claim 1 , further comprising a display device that displays a rendered image constructed by the rendering processor.

7 . The slit lamp microscope of claim 1 , wherein the controller is further configured to control the photography system to perform sensitivity adjustment.

8 . The slit lamp microscope of claim 1 , wherein the adjusting relative positions of the illumination system and the photography system is performed using the movement mechanism to adjust an angle formed by the optical axes of the illumination system and the photography system.

9 . An ophthalmic system comprising a slit lamp microscope, an information processing apparatus, and an image interpretation computer terminal, wherein

the slit lamp microscope includes:

a controller;

a scanner configured to scan a crystalline lens including opaque areas of an anterior segment of a subject's eye with slit light to collect a plurality of cross sectional images, the scanner including an illumination system configured to project the slit light onto at least the crystalline lens, a photography system configured to perform photography of the crystalline lens from a direction different from the illumination system, and a movement mechanism configured to move the illumination system and the photography system, and the controller is configured to control the illumination system to perform adjustment of intensity of the slit light; and

a transmission device that transmits first transmission information that includes at least the plurality of cross sectional images collected by the scanner to the information processing apparatus via a communication line,

the information processing apparatus includes:

a reception device that receives the first transmission information,

a memory in which the first transmission information is stored; and

a transmission device that transmits second transmission information that includes at least the plurality of cross sectional images included in the first transmission information to the image interpretation computer terminal via a communication line, and

the image interpretation computer terminal includes:

a reception device that receives the second transmission information;

a rendering processor configured to apply rendering to a three dimensional image, in which the opaque areas are depicted, created from the plurality of cross sectional images included in the second transmission information;

a user interface operated by a user to perform interpretation of a rendered image constructed by the rendering processor, and

a transmission device that transmits third transmission information that includes at least information input using the user interface to the information processing apparatus via a communication line,

wherein the information processing apparatus receives the third transmission information by the reception device thereof, associates the third transmission information with the first transmission information, and stores the third transmission information in the memory, and

the ophthalmic system further comprising:

a reconstruction processor configured to apply three dimensional reconstruction to the plurality of cross sectional images collected by the scanner; and

a segmentation processor configured to apply segmentation to a three dimensional reconstructed image constructed by the reconstruction processor to identify a crystalline lens region corresponding to at least part of the crystalline lens from the three dimensional reconstructed image,

wherein the rendering processor is further configured to apply rendering to the crystalline lens region in which the opaque areas are depicted,

wherein the photography system includes an optical system configured to direct light coming from the anterior segment onto which the slit light is projected, and an image sensor including a light detecting plane configured to receive the light directed by the optical system,

wherein a subject plane along an optical axis of the illumination system, the optical system, and the light detecting plane satisfy a Scheimpflug condition, and

the scanner is configured to scan the crystalline lens in a state in which focus of the photography system is on an entirety of at least an area from a cornea of the anterior segment to the crystalline lens by adjusting relative positions of the illumination system and the photography system using the movement mechanism.

10 . An ophthalmic system comprising a slit lamp microscope, an information processing apparatus, and an image interpretation apparatus, wherein

the slit lamp microscope includes:

a controller;

a scanner configured to scan a crystalline lens including opaque areas of an anterior segment of a subject's eye with slit light to collect a plurality of cross sectional images, the scanner including an illumination system configured to project the slit light onto at least the crystalline lens, a photography system configured to perform photography of at least the crystalline lens from a direction different from the illumination system, and a movement mechanism configured to move the illumination system and the photography system, and the controller is configured to control the illumination system to perform adjustment of intensity of the slit light; and

a transmission device that transmits first transmission information that includes at least the plurality of cross sectional images collected by the scanner to the information processing apparatus via a communication line,

the information processing apparatus includes:

a reception device that receives the first transmission information;

a memory in which the first transmission information is stored; and

a transmission device that transmits second transmission information that includes at least the plurality of cross sectional images included in the first transmission information to the image interpretation apparatus via a communication line, and

the image interpretation apparatus includes:

a reception device that receives the second transmission information;

a rendering processor configured to apply rendering to a three dimensional image, in which the opaque areas are depicted, created from the plurality of cross sectional images included in the second transmission information;

an image interpretation processor configured to perform interpretation of a rendered image constructed by the rendering processor; and

a transmission device that transmits fourth transmission information that includes at least information generated by the image interpretation processor to the information processing apparatus via a communication line,

wherein the information processing apparatus receives the fourth transmission information by the reception device thereof, associates the fourth transmission information with the first transmission information, and stores the fourth transmission information in the memory, and

the ophthalmic system further comprising:

a reconstruction processor configured to apply three dimensional reconstruction to the plurality of cross sectional images collected by the scanner; and

a segmentation processor configured to apply segmentation to a three dimensional reconstructed image constructed by the reconstruction processor to identify a crystalline lens region corresponding to at least part of the crystalline lens from the three dimensional reconstructed image,

wherein the rendering processor is further configured to apply rendering to the crystalline lens region in which the opaque areas are depicted,

wherein the photography system includes an optical system configured to direct light coming from the anterior segment onto which the slit light is projected, and an image sensor including a light detecting plane configured to receive the light directed by the optical system,

wherein a subject plane along an optical axis of the illumination system, the optical system, and the light detecting plane satisfy a Scheimpflug condition, and

the scanner is configured to scan the crystalline lens in a state in which focus of the photography system is on an entirety of at least an area from a cornea of the anterior segment to the crystalline lens by adjusting relative positions of the illumination system and the photography system using the movement mechanism.

11 . A method of controlling a slit lamp microscope that includes a processor, a controller, and a scanner, the method comprising:

causing the scanner to scan a crystalline lens including opaque areas of an anterior segment of a subject's eye with slit light to collect a plurality of cross sectional images, the scanner including an illumination system configured to project the slit light onto at least the crystalline lens, a photography system configured to perform photography of at least the crystalline lens from a direction different from the illumination system, and a movement mechanism configured to move the illumination system and the photography system;

causing the processor to execute a process of applying three dimensional reconstruction to the plurality of cross sectional images collected by the scanner;

causing the processor to execute a process of segmentation to a three dimensional reconstructed image constructed by the three dimensional reconstruction to identify a crystalline lens region corresponding to at least part of the crystalline lens from the three dimensional reconstructed image;

causing the processor to execute a process of applying rendering to the crystalline lens region in which the opaque areas are depicted; and

causing the controller to control the illumination system to perform adjustment of intensity of the slit light,

wherein the photography system includes an optical system configured to direct light coming from the anterior segment onto which the slit light is projected, and an image sensor including a light detecting plane configured to receive the light directed by the optical system,

wherein a subject plane along an optical axis of the illumination system, the optical system, and the light detecting plane satisfy a Scheimpflug condition, and

the method further includes causing the scanner to scan the crystalline lens in a state in which focus of the photography system is on an entirety of at least an area from a cornea of the anterior segment to the crystalline lens by adjusting relative positions of the illumination system and the photography system using the movement mechanism.

12 . A computer-readable non-transitory recording medium storing a program configured to cause a computer to execute the method of claim 11 .