Methods and compositions for slowing an aging process in a human or an animal
View Patent ↗The present disclosure provides muscle regenerative compositions comprising an extracted mineral element composition, which slow the aging process. The disclosure provides methods of slowing an aging process in a human. For example, a method can comprise administering to a human or animal having an age-associated muscle wasting disorder an effective amount of a muscle regenerative composition comprising an extracted mineral element composition.
1 . A method of slowing an aging process in a human, comprising:
administering to a human having sarcopenia an effective amount of a muscle regenerative composition comprising an extracted mineral element composition,
wherein the extracted mineral element composition comprises calcium, chlorine, magnesium, manganese, phosphorous, potassium, silicon, and sodium extracted from at least one of: a clay soil, a mixture of clay soils, and a mixture of clay soils and leonardite; and
wherein said administration increases cellular metabolism by at least 20% in the human, thereby reducing muscle degeneration in the human having sarcopenia; and
wherein the muscle regenerative composition comprises at least 100 milligrams of the extracted mineral element composition per milliliter of the muscle regenerative composition.
2 . The method of claim 1 , further comprising inhibiting muscle mass loss or a deleterious change in muscle tone in the human having sarcopenia.
3 . The method of claim 1 , further comprising modulating a MYH2 gene to upregulate and increase expression of MHCIIa protein by at least 3-fold above a baseline level in at least one muscle cell in the human having sarcopenia, thereby increasing muscle mass in the human having sarcopenia.
4 . The method of claim 1 , further comprising increasing muscle cell protein production in at least one muscle cell in the human having sarcopenia by about 20%.
5 . The method of claim 1 , further comprising upregulating gene expression of MYH2 to increase expression of MHCIIa protein by at least 4-fold above a baseline level in at least one muscle cell in the human having sarcopenia, thereby increasing muscle mass in the human having sarcopenia.
6 . The method of claim 1 further comprising reversing the free radical-induced suppression of MYH2 expression in at least one muscle cell in the human having sarcopenia; and restoring a pre-senescence production level of MHCIIa protein in the at least one muscle cell.
7 . The method of claim 1 , wherein the muscle regenerative composition further comprises β-hydroxy-βmethylbutyrate (HMB).
8 . The method of claim 1 , wherein the muscle regenerative composition is combined with a foodstuff.
9 . The method of claim 1 , wherein the muscle regenerative composition is combined with a beverage.
10 . The method of claim 1 , wherein the muscle regenerative composition is combined with a topical.
11 . The method of claim 1 , wherein the extracted mineral element composition further comprises at least sixty micro mineral elements extracted from at least one of: a clay soil, a mixture of clay soils, and a mixture of clay soils and leonardite.
12 . The method of claim 11 , wherein the at least sixty micro mineral elements comprise aluminum, antimony, arsenic, barium, beryllium, bismuth, boron, bromine, cadmium, cerium, cesium, chromium, cobalt, copper, dysprosium, erbium, europium, fluorine, gadolinium, gold, hafnium, holmium, iodine, indium, iridium, iron, lanthanum, lead, lithium, lutetium, mercury, molybdenum, neodymium, nickel, niobium, palladium, platinum, praseodymium, rhenium, rhodium, rubidium, ruthenium, samarium, scandium, selenium, silver, strontium, sulfur, tantalum, terbium, tellurium, thallium, thorium, thulium, tin, titanium, tungsten, vanadium, ytterbium, yttrium, zinc, and zirconium.
13 . The method of claim 1 , wherein the extracted mineral element composition comprises a concentration of the calcium of about 16 mg/ml, a concentration of the chlorine of about 1.7 mg/ml, a concentration of the magnesium of about 2 mg/ml, a concentration of the manganese of about 3 mg/ml, a concentration of the phosphorous of about 0.9 mg/ml, a concentration of the potassium of about 2.4 mg/ml, a concentration of the silicon of about 0.7 mg/ml, and a concentration of the sodium of about 4 mg/ml.
14 . The method of claim 1 , wherein the extracted mineral element composition comprises a concentration of the calcium of about 8 mg/ml, a concentration of the chlorine of about 0.8 mg/ml, a concentration of the magnesium of about 1 mg/ml, a concentration of the manganese of about 1.5 mg/ml, a concentration of the phosphorous of about 0.43 mg/ml, a concentration of the potassium of about 1.2 mg/ml, a concentration of the silicon of about 0.36 mg/ml, and a concentration of the sodium of about 2 mg/ml.
15 . The method of claim 1 , wherein the extracted mineral element composition comprises a concentration of the calcium of about 2900 mg/L, a concentration of the chlorine of about 170 mg/L, a concentration of the magnesium of about 460 mg/L, a concentration of the manganese of about 8.6 mg/L, a concentration of the phosphorous of about 200 mg/L, a concentration of the potassium of about 220 mg/L, a concentration of the silicon of about 130 mg/L, and a concentration of the sodium of about 720 mg/L.
16 . The method of claim 1 , wherein the extracted mineral element composition comprises a weight percent of the calcium of about 8%, a weight percent of the chlorine of about 0.8%, a weight percent of the magnesium of about 1%, a weight percent of the manganese of about 0.002%, a weight percent of the phosphorous of about 0.4%, a weight percent of the potassium of about 1%, a weight percent of the silicon of about 0.4%, and a weight percent of the sodium of about 2%.
17 . The method of claim 1 , wherein the effective amount of a muscle regenerative composition comprises at least 0.8% calcium, at least 0.08% chlorine, at least 0.1% magnesium, at least 0.0002% manganese, at least 0.04% phosphorous, at least 0.1% potassium, at least 0.04% silicon, and at least 0.2% sodium.