IP Library Granted Patent US 12,702,361
Granted Patent B2
US 12,702,361 · App. 18/179,594 · Granted Aug 11, 2026

Systems and methods for dynamically and intelligently monitoring a host's glycemic condition after an alert is triggered

Inventors: Hari Hampapuram (Beaverton, OR); Anna Leigh Davis (Cardiff by the Sea, CA); Naresh C. Bhavaraju (San Diego, CA); Apurv Ullas Kamath (San Diego, CA); Claudio Cobelli (Padua, IT); Giovanni Sparacino (Padua, IT); Andrea Facchinetti (Padua, IT); Chiara Zecchin (Pernumia, IT)
Assignee: Dexcom, Inc.
A61B5/746A61B5/0004A61B5/0022A61B5/0031A61B5/14503A61B5/14532A61B5/4848A61B5/4866A61B5/7221A61B5/7275A61B5/002
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Quick Facts
Patent No.
US 12,702,361
App. No.
18/179,594
Granted
Aug 11, 2026
Kind
B2
Abstract

Systems and methods for providing sensitive and specific alarms indicative of glycemic condition are provided herein. In an embodiment, a method of processing sensor data by a continuous analyte sensor includes: evaluating sensor data using a first function to determine whether a real time glucose value meets a first threshold; evaluating sensor data using a second function to determine whether a predicted glucose value meets a second threshold; activating a hypoglycemic indicator if either the first threshold is met or if the second threshold is predicted to be met; and providing an output based on the activated hypoglycemic indicator.

Claims (69)

1 . A method for activating glycemic indicators, the method comprising:

evaluating a selection of glucose sensor data using a first function to determine whether a real time glucose value meets or crosses a user settable real time threshold value;

evaluating the same selection of glucose sensor data using a second function different from the first function to determine whether a predicted glucose value meets or crosses a predictive threshold value within a fixed prediction horizon, wherein the user settable real time threshold value is different from the predictive threshold value;

providing a first output including a first glycemic indicator when the user settable real time threshold value is met or crossed; and

providing a second output including a second glycemic indicator when the predicted glucose value meets or crosses the predictive threshold value within the fixed prediction horizon.

2 . The method of claim 1 , wherein the fixed prediction horizon is not settable by a user.

3 . The method of claim 1 , wherein the fixed prediction horizon is preset.

4 . The method of claim 3 , wherein:

the selection of glucose sensor data is a value representative of one or more data points averaged over a predetermined time period.

5 . The method of claim 1 , wherein:

the user settable real time threshold value defines an upper glucose value for a user;

the predictive threshold value defines an upper glucose value for the user; and

the first and second glycemic indicators are hyperglycemic indicators.

6 . The method of claim 1 , wherein:

the user settable real time threshold value defines a lower glucose value for a user;

the predictive threshold value defines a lower glucose value for the user; and

the first and second glycemic indicators are hypoglycemic indicators.

7 . A non-transitory computer-readable medium for storing instructions that, when executed by a processor, cause the processor to perform a method for activating glycemic indicators, the method comprising:

evaluating a selection of glucose sensor data using a first function to determine whether a real time glucose value meets or crosses a user settable real time threshold value;

evaluating the same selection of glucose sensor data using a second function different from the first function to determine whether a predicted glucose value meets or crosses a predictive threshold value within a fixed prediction horizon, wherein the user settable real time threshold value is different from the predictive threshold value;

providing a first output including a first glycemic indicator when the user settable real time threshold value is met or crossed; and

providing a second output including a second glycemic indicator when the predicted glucose value meets or crosses the predictive threshold value within the fixed prediction horizon.

8 . The non-transitory computer-readable medium of claim 7 , wherein the fixed prediction horizon is 20 minutes or less.

9 . The non-transitory computer-readable medium of claim 7 , wherein the fixed prediction horizon is not settable by a user.

10 . The non-transitory computer-readable medium of claim 7 , wherein the fixed prediction horizon is preset.

11 . The non-transitory computer-readable medium of claim 10 , wherein the fixed prediction horizon is preset at a factory.

12 . The non-transitory computer-readable medium of claim 10 , wherein:

the user settable real time threshold value defines an upper glucose value for a user;

the predictive threshold value defines an upper glucose value for the user; and

the first and second glycemic indicators are hyperglycemic indicators.

13 . The non-transitory computer-readable medium of claim 10 , wherein:

the user settable real time threshold value defines a lower glucose value for a user;

the predictive threshold value defines a lower glucose value for the user; and

the first and second glycemic indicators are hypoglycemic indicators.

14 . A system for activating glycemic indicators, the system comprising:

a memory configured to store glucose sensor data from a transcutaneous glucose sensor; and

a processor, coupled to the memory, the processor configured to:

evaluate a selection of the glucose sensor data using a first function to determine whether a real time glucose value meets or crosses a user settable real time threshold value,

evaluate the same selection of glucose sensor data using a second function different from the first function to determine whether a predicted glucose value meets or crosses a predictive threshold value within a fixed prediction horizon, wherein the user settable real time threshold value is different from the predictive threshold value,

provide a first output including a first glycemic indicator when the user settable real time threshold value is met or crossed, and

provide a second output including a second glycemic indicator when the predicted glucose value meets or crosses the predictive threshold value within the fixed prediction horizon.

15 . The system of claim 14 , wherein the fixed prediction horizon is 20 minutes or less.

16 . The system of claim 14 , wherein the fixed prediction horizon is not settable by a user.

17 . The system of claim 14 , wherein the fixed prediction horizon is preset at a factory.

18 . The system of claim 14 , wherein:

the user settable real time threshold value defines an upper glucose value for a user;

the predictive threshold value defines an upper glucose value for the user; and

the first and second glycemic indicators are hyperglycemic indicators.

19 . The system of claim 14 , wherein:

the user settable real time threshold value defines a lower glucose value for a user;

the predictive threshold value defines a lower glucose value for the user; and

the first and second glycemic indicators are hypoglycemic indicators.

20 . A method for activating glycemic indicators, the method comprising:

evaluating a selection of glucose sensor data to determine whether a real time glucose value meets or crosses a user settable real time threshold value, wherein the selection of glucose sensor data includes a value representative of one or more data points averaged over a predetermined time period;

evaluating the same selection of glucose sensor data to determine whether a predicted glucose value meets or crosses a predictive threshold value within a preset fixed prediction horizon, wherein the user settable real time threshold value is different from the predictive threshold value;

providing a first output including a first glycemic indicator when the user settable real time threshold value is met or crossed; and

providing a second output including a second glycemic indicator when the predicted glucose value meets or crosses the predictive threshold value within the preset fixed prediction horizon.

21 . A non-transitory computer-readable medium for storing instructions that, when executed by a processor, cause the processor to perform a method for activating glycemic indicators, the method comprising:

evaluating a selection of glucose sensor data to determine whether a real time glucose value meets or crosses a user settable real time threshold value, wherein the selection of glucose sensor data includes a value representative of one or more data points averaged over a predetermined time period;

evaluating the same selection of glucose sensor data to determine whether a predicted glucose value meets or crosses a predictive threshold value within a preset fixed prediction horizon, wherein the user settable real time threshold value is different from the predictive threshold value;

providing a first output including a first glycemic indicator when the user settable real time threshold value is met or crossed; and

providing a second output including a second glycemic indicator when the predicted glucose value meets or crosses the predictive threshold value within the preset fixed prediction horizon.

22 . A system for activating glycemic indicators, the system comprising:

a memory configured to store glucose sensor data from a transcutaneous glucose sensor; and

a processor, coupled to the memory, the processor configured to:

evaluate a selection of glucose sensor data to determine whether a real time glucose value meets or crosses a user settable real time threshold value, wherein the selection of glucose sensor data includes a value representative of one or more data points averaged over a predetermined time period;

evaluate the same selection of glucose sensor data to determine whether a predicted glucose value meets or crosses a predictive threshold value within a preset fixed prediction horizon, wherein the user settable real time threshold value is different from the predictive threshold value;

provide a first output including a first glycemic indicator when the user settable real time threshold value is met or crossed; and

provide a second output including a second glycemic indicator when the predicted glucose value meets or crosses the predictive threshold value within the preset fixed prediction horizon.