Supported nicotine composition
The present invention relates to a composition comprising nicotine and/or nicotine salt, and calcium silicate, wherein the composition is in a pouch, wherein the pouch is intended to be placed in the mouth.
1 . A premix composition comprising calcium silicate in a range of 20 wt % to 60 wt % and nicotine in a range of 10 wt % to 60 wt %, wherein the amount of nicotine is present as nicotine and/or an equivalent amount of nicotine provided as a nicotine salt.
2 . A premix composition according to claim 1 , wherein the ratio of nicotine, and/or nicotine salt to calcium silicate by weight is in the range of 5%:95% to 75%:25%, wherein the amount of nicotine is present as nicotine and/or an equivalent amount of nicotine provided as a nicotine salt.
3 . A premix composition according to claim 1 further comprising water.
4 . A premix composition according to claim 1 , wherein the premix composition further comprises an acid, ethanol, glycerol or any combination thereof.
5 . A premix composition according to claim 4 , wherein the acid is selected from the group consisting of pyruvic acid, benzoic acid, levulinic acid, citric acid, gluconic acid, glucuronic acid, ribonic acid, arabinonic acid or galactonic acid.
6 . A premix composition according to claim 1 , wherein a form of administration is selected from: pouch, a heat-not-burn device, patch, a lozenge, a troche, a pill, a capsule, a tablet or a chewing gum.
7 . A method for preparing a premix composition comprising mixing calcium silicate in a range of 20 wt % to 60 wt % calcium silicate and nicotine in a range of 10 wt % to 60 wt %, wherein the amount of nicotine is present as nicotine and/or an equivalent amount of nicotine provided as a nicotine salt.
8 . A method according to claim 7 , wherein the method further comprises mixing the nicotine and/or a nicotine salt with an acid, ethanol, carbon dioxide, glycerol or a combination thereof to form a solution before mixing the solution with the calcium silicate.
9 . A method according to claim 7 , the method further comprising mixing in water.
10 . A method according to claim 9 , wherein 5 wt % to 30 wt % water is mixed in.
11 . A method according to claim 8 , wherein the nicotine and/or a nicotine salt is mixed with carbon dioxide and, optionally, an acid, ethanol, glycerol or a combination thereof to form a solution before mixing the solution with the calcium silicate.
12 . A method according to claim 11 , wherein the solution is homogenous before mixing with calcium silicate.
13 . A method according to claim 11 , wherein the solution is introduced to the calcium silicate incrementally.
14 . A method according to claim 11 , wherein mixing continues until a free-flowing powder is prepared.