IP Library Granted Patent US 12708136
Granted Patent B2
US 12708136 · App. 18/286,925 · Granted Aug 18, 2026

Supported nicotine composition

Inventors: Vinod Kumar Reddy Bondu (London, GB); Raymond McCague (London, GB); William Jackson (London, GB); George Cassels-Smith (London, GB); Ashok Srinivasan Narasimhan (London, GB)
Assignee: Zanoprima Lifesciences Limited
A24B15/16A23G4/064A23G4/126A24B13/00A24B15/32A24B15/42
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Quick Facts
Patent No.
US 12708136
App. No.
18/286,925
Granted
Aug 18, 2026
Kind
B2
Abstract

The present invention relates to a composition comprising nicotine and/or nicotine salt, and calcium silicate, wherein the composition is in a pouch, wherein the pouch is intended to be placed in the mouth.

Claims (14)

1 . A premix composition comprising calcium silicate in a range of 20 wt % to 60 wt % and nicotine in a range of 10 wt % to 60 wt %, wherein the amount of nicotine is present as nicotine and/or an equivalent amount of nicotine provided as a nicotine salt.

2 . A premix composition according to claim 1 , wherein the ratio of nicotine, and/or nicotine salt to calcium silicate by weight is in the range of 5%:95% to 75%:25%, wherein the amount of nicotine is present as nicotine and/or an equivalent amount of nicotine provided as a nicotine salt.

3 . A premix composition according to claim 1 further comprising water.

4 . A premix composition according to claim 1 , wherein the premix composition further comprises an acid, ethanol, glycerol or any combination thereof.

5 . A premix composition according to claim 4 , wherein the acid is selected from the group consisting of pyruvic acid, benzoic acid, levulinic acid, citric acid, gluconic acid, glucuronic acid, ribonic acid, arabinonic acid or galactonic acid.

6 . A premix composition according to claim 1 , wherein a form of administration is selected from: pouch, a heat-not-burn device, patch, a lozenge, a troche, a pill, a capsule, a tablet or a chewing gum.

7 . A method for preparing a premix composition comprising mixing calcium silicate in a range of 20 wt % to 60 wt % calcium silicate and nicotine in a range of 10 wt % to 60 wt %, wherein the amount of nicotine is present as nicotine and/or an equivalent amount of nicotine provided as a nicotine salt.

8 . A method according to claim 7 , wherein the method further comprises mixing the nicotine and/or a nicotine salt with an acid, ethanol, carbon dioxide, glycerol or a combination thereof to form a solution before mixing the solution with the calcium silicate.

9 . A method according to claim 7 , the method further comprising mixing in water.

10 . A method according to claim 9 , wherein 5 wt % to 30 wt % water is mixed in.

11 . A method according to claim 8 , wherein the nicotine and/or a nicotine salt is mixed with carbon dioxide and, optionally, an acid, ethanol, glycerol or a combination thereof to form a solution before mixing the solution with the calcium silicate.

12 . A method according to claim 11 , wherein the solution is homogenous before mixing with calcium silicate.

13 . A method according to claim 11 , wherein the solution is introduced to the calcium silicate incrementally.

14 . A method according to claim 11 , wherein mixing continues until a free-flowing powder is prepared.