IP Library Granted Patent US 12708676
Granted Patent B2
US 12708676 · App. 18/193,570 · Granted Aug 18, 2026

Phosphate compounds for detecting neurological disorders

Inventors: Stella Sarraf (Beverly Hills, CA); Lyndsay M. Randolph (San Diego, CA); Suhail Rasool (San Diego, CA)
Assignee: Amydis, Inc.
A61K49/0021A61K9/0048A61P25/16A61P25/28C07F9/59
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Quick Facts
Patent No.
US 12708676
App. No.
18/193,570
Granted
Aug 18, 2026
Kind
B2
Abstract

Provided herein are compounds, methods and compositions for determining whether a patient has a neurological disease or disorder is provided, comprising detecting the presence of a detectable target protein, or an accumulated mass thereof, for example, amyloid beta protein or phosphorylated tau protein, or an accumulated mass thereof, in a tissue or a sample of the patient. The detecting may comprise contacting the target protein with a compound described herein.

Claims (4)

1 . A compound represented by formula:

or a pharmaceutically acceptable salt thereof.

2 . A pharmaceutical composition comprising the compound of claim 1 , or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier.

3 . The compound of claim 1 , wherein the salt is a diammonium salt.