Internal cold plasma system
A system including an internal cold plasma system, including an internal cold plasma applicator configured to couple to a surface surrounding a cavity and to produce a cold plasma between the internal cold plasma applicator and the surface.
1 . An internal cold plasma system comprising:
an applicator configured to be disposed within a cavity of a patient and to produce a cold plasma only between an outer surface of the applicator and a surface of the patient, wherein the applicator is configured to be navigated through an anatomical passage of the patient into the cavity of the patient,
wherein the applicator comprises a flexible conduit configured to enable the applicator to conform to different cavities of different patients,
wherein the flexible conduit has a first passage extending between a first end and a second end, wherein the first passage contains a conductive fluid, wherein the flexible conduit is defined by a wall made of a dielectric material, and wherein the dielectric material is configured to enable an electrical signal to build charge inside the flexible conduit,
wherein the applicator further comprises a second conduit having a second passage, wherein the second passage is configured to function as a dielectric by carrying additional dielectric material or being empty, and
wherein the applicator further comprises a plurality of apertures arranged about a circumference of the outer surface of the applicator, wherein each aperture of the plurality of apertures is in communication with the second passage.
2 . The system of claim 1 , wherein the applicator is a catheter that is configured to be inserted into a urethra of the patient.
3 . The system of claim 1 , wherein the dielectric material of the wall of the flexible conduit is configured to enable the electrical signal to build the charge inside the flexible conduit until a sufficient amount of charge builds whereupon the electrical signal crosses through the wall between the first end and the second end and produces the cold plasma from fluid within a gap between the wall and the surface of the patient.
4 . The system of claim 1 , wherein the second conduit surrounds the flexible conduit, and the second passage is disposed between the flexible conduit and the second conduit.
5 . The system of claim 3 , further comprising an electrode that rests within the first passage.
6 . The system of claim 3 , wherein the first end of the flexible conduit comprises a tapered end that facilitates insertion into the cavity of the patient.
7 . The system of claim 1 , further comprising a plurality of spacers configured to separate a cold plasma-generating surface of the flexible conduit from the surface of the patient.
8 . The system of claim 1 , further comprising a controller configured to produce the electrical signal that forms the cold plasma with the applicator from fluid within a gap between the outer surface of the applicator and the surface of the patient.
9 . The system of claim 2 , wherein the flexible conduit comprises an inflatable portion, wherein the inflatable portion is configured to block retraction and enable secure placement of the catheter after insertion into the urethra of the patient.
10 . The system of claim 3 , wherein the applicator is configured to use the conductive fluid to carry the electrical signal that generates the cold plasma.
11 . A method comprising:
positioning the applicator of the system of claim 8 within the cavity of the patient;
producing the electrical signal with the controller, and
generating the cold plasma using the electrical signal, wherein the conductive fluid conducts the electrical signal toward the patient.
12 . The method of claim 11 , further comprising pumping a gas from a gas source to the applicator.
13 . The method of claim 11 , wherein the conductive fluid is a conductive bodily fluid of the patient.
14 . The method of claim 13 , wherein the conductive bodily fluid is urine.
15 . The method of claim 11 , wherein the conductive fluid comprises saline.
16 . The method of claim 11 , wherein the applicator of the system is a catheter, and wherein the applicator is positioned within a urethra the anatomical passage of the patient, wherein the anatomical passage is a urethra of the patient.
17 . The method of claim 16 , wherein the conductive fluid is urine of the patient.
18 . The method of claim 16 , further comprising inflating an inflatable portion of the flexible conduit to block retraction and secure the catheter within the urethra of the patient.
19 . An internal cold plasma system comprising:
an applicator configured to be disposed within a cavity of a patient and to produce a cold plasma only between an outer surface of the applicator and a surface of the patient, wherein the applicator is configured to be navigated through an anatomical passage of the patient into the cavity of the patient,
wherein the applicator comprises a flexible conduit configured to enable the applicator to conform to different cavities of different patients,
wherein the flexible conduit has a first passage extending between a first end and a second end, wherein the first passage contains a conductive fluid, wherein the flexible conduit is defined by a wall made of a dielectric material, and wherein the dielectric material is configured to enable an electrical signal to build charge inside the flexible conduit,
wherein the applicator further comprises a second conduit having a second passage, wherein the second passage is configured to function as a dielectric by carrying additional dielectric material or being empty, and
wherein the flexible conduit surrounds the second conduit, and wherein the first passage is disposed between the flexible conduit and the second conduit.
20 . The internal cold plasma system of claim 1 , wherein the plurality of apertures comprises a first aperture and a second aperture that is circumferentially spaced from the first aperture about the outer surface of the applicator.