Three-dimensional sample scanning system
System for sample scanning comprising a movable sample holder, an optical device, a base element, at least first and second displacement means, and a camera for receiving a scattered light by a sample, wherein the optical device and the element are located between the first stage and the second stage and the first direction is perpendicular to the second direction.
1 . A system for scanning a sample comprising:
a sample holder configured to hold a sample;
an optical device comprising a light source for emitting light towards the sample holder, an emitted light filter plate comprising a first array of filters, and a scattered light filter plate comprising a second array of filters;
a base element comprising a first case extending along an optical path of the light emitted by the light source towards the sample holder and a second case extending along an optical path of light scattered by a sample held in the sample holder;
wherein the emitted light filter plate is positioned along the optical path of the emitted light and the scattered light filter plate is positioned along the optical path of the scattered light; and
wherein the first case is fixed with respect to the second case;
first displacement means coupled to at least one of the optical device and the base element for relatively moving the emitted light filter plate and the scattered light filter plate of the optical device with respect to the base element along a first direction; and
second displacement means, which is distinct from the first displacement means and is coupled to at least one of the base element and the sample holder for relatively moving the base element and the sample holder with respect to each other along the first direction, such that the optical path of the emitted light moves with respect to a sample held in the sample holder.
2 . The system of claim 1 , wherein the first case extends along a first longitudinal axis and the second case extends along a second longitudinal axis, the first longitudinal axis and the second longitudinal axis forming an angle lower than 90°.
3 . The system of claim 2 , wherein said angle is between 30° and 45°.
4 . The system of claim 1 , wherein the first and second displacement means comprise slide links, which are parallel to each other and extend along the first direction (X).
5 . The system of claim 1 , further comprising an additional displacement means coupled to the sample holder for moving the sample holder with respect to the base element in a second direction.
6 . The system of claim 5 , wherein the second direction is perpendicular to the first direction.
7 . The system of claim 1 , wherein the first displacement means is configured to move the optical device with respect to the base element and the second displacement means is configured to move the base element with respect to the sample holder.
8 . The system of claim 1 , wherein the sample holder comprises at least one sample slot.
9 . The system of claim 1 , wherein the optical device further comprises a main plate that extends in a plane perpendicular to the sample holder and from which extends, along the first direction, the light source, the emitted light filter plate, and the scattered light filter plate.
10 . The system of claim 1 , wherein the first case comprises a first slit that extends along the first direction and is configured to receive the emitted light filter plate, and the second case comprises a second slit that extends along the first direction and is configured to receive the scattered light filter plate, such that the emitted light filter plate and the scattered light filter plate slide inside the first and second slits to align a pair of emitted and scattered light filters with the optical path of the emitted light and the optical path of the scattered light.
11 . The system of claim 1 , wherein the emitted light filter plate comprises a number of emitted light filters and the scattered light filter plate comprises the same number of scattered light filters.
12 . The system of claim 1 , further comprising a bright field light source coupled to the second case and configured to emit a bright light towards a sample held in the sample holder.
13 . The system of claim 12 , wherein the optical axis of the bright field light source and the optical axis of the light source are symmetrical with respect to the optical path of the scattered light.
14 . The system of claim 1 , wherein the optical device and the base element are connected to a second stage via the first and second displacement means.
15 . The system of claim 14 , wherein the optical device and the base element are located between the sample holder and the second stage.
16 . The system of claim 1 , further comprising an electronic control unit for controlling movement of at least one of the optical device, the base element, and the sample holder.
17 . The system of claim 1 , further comprising a camera for receiving light scattered by a sample held in the sample holder.
18 . The system of claim 1 , wherein the emitted light filter plate is fixed with respect to the scattered light filter plate and the light source.