Multi-modal crypto/bio-human-machine interface
The present embodiments relate to a multimodal cryptographic bio-human machine interface (“CB-HMI”), which seamlessly translates the user's touch-based entries into encrypted biochemical, biophysical, and biometric indices. The CB-HMI features thin hydrogel-coated chemical sensors and inference algorithms to non-invasively and inconspicuously acquire biochemical indices such as circulating molecules that partition onto the skin (here, ethanol and acetaminophen). Additionally, the CB-HMI hosts physical sensors and associated algorithms to simultaneously acquire the user's heart rate, blood oxygen level, and fingerprint minutiae pattern. Additional or alternative embodiments include a touch-based non-invasive monitoring solution for lithium pharmacotherapy management. The system is constructed based on a thin organohydrogel-coated lithium ion-selective electrode (TOH-ISE), where the TOH coating was engineered to render stabilized conditions for sensing. In particular, by adopting a water glycerol bi-solvent matrix, the gel features antidehydration property, rendering a controlled micro-environment for the ISE to condition and minimized the signal drift.
1 . A device comprising:
a multimodal cryptographic bio-human machine interface (“CB-HMI”) configured to translate a user's touch-based entries and/or other biomarkers into encrypted biometric indices, the CB-HMI including a service activator that receives the encrypted biometric indices and determines whether to activate a service for the user based on an analysis of biomarkers and identity information included in the encrypted biometric indices.
2 . The device of claim 1 , wherein the CB-HMI further includes thin hydrogel-coated chemical sensors and inference algorithms to non-invasively acquire biomarkers and/or biochemical indices such as circulating molecules that partition onto the skin.
3 . The device of claim 2 , wherein the circulating molecules comprise one or both of ethanol and acetaminophen.
4 . The device of claim 1 , wherein the CB-HMI further includes physical sensors and associated algorithms to simultaneously acquire one or more of the user's heart rate, blood oxygen level, blood pressure, respiratory rate, and fingerprint minutiae pattern.
5 . The device of claim 1 , wherein the CB-HMI is further configured to acquire physiologically-relevant readouts of target bio-indices and to biometrically encrypt and decrypt these bio-indices in-situ using a fingerprint sensor.
6 . The device of claim 1 , wherein the service is associated with driving safety and medication use.
7 . The device of claim 6 wherein the service activator is included in a vehicle activation system.
8 . The device of claim 6 wherein the service activator is included in a medication dispensing system.
9 . The device of claim 1 , wherein the CB-HMI includes a gel-coated lithium sensing interface to collect and analyze partitioned lithium ions on fingertips in-situ.
10 . The device of claim 1 , wherein the biomarkers included in the analysis include one or more of the user's heart rate, blood oxygen level, blood pressure and respiratory rate.
11 . The device of claim 1 , wherein the biomarkers included in the analysis include a detected level of ethanol in the user's fingertip.
12 . The device of claim 11 , wherein the detected level of ethanol is determined from an analysis of the user's sweat.
13 . The device of claim 1 , wherein the biomarkers included in the analysis include a detected level of acetaminophen in the user's fingertip.
14 . The device of claim 13 , wherein the detected level of acetaminophen is determined from an analysis of the user's sweat.
15 . A device comprising:
a touch-based non-invasive lithium monitoring solution, including a gel-coated lithium sensing interface to collect and analyze partitioned lithium ions on fingertips in-situ.
16 . The device of claim 15 , wherein the interface comprises a thin organohydrogel-coated lithium ion-selective electrode (TOH-ISE), wherein the TOH simultaneously addresses stability challenges associated with the sensing interface.
17 . The device of claim 16 , wherein the TOH comprises a water-glycerol bi-solvent matrix, having an anti-dehydration property.
18 . The device of claim 16 , wherein when coupled with a lithium ISE, the TOH coating serves as a controlled micro-environment to condition the ISE in-situ.
19 . The device of claim 16 , wherein the TOH-ISE includes a ISE-specific signal interpretation framework that is capable of extracting the lithium flux information from touch-based readouts.