Systems and methods for MRI guided trans-orifice and transperineal intervention apparatus with adjustable biopsy needle insertion
View Patent ↗An intervention apparatus is described having a probe with an orifice insertion portion, the insertion portion being configured for insertion into an orifice of a patient. The apparatus also having an intervention tool securement and adjustment mechanism removably attached to the probe. The probe providing support to hold the mechanism in a position relative to the patient, and the adjustment mechanism providing adjustment of an entry point and an angle of entry for an intervention tool to the patient. In embodiments, magnetic resonance imaging, trans-orifice intervention and transperineal intervention are described. Methods for imaging and/or intervention are also described.
1. An intervention apparatus comprising:
a probe having an orifice insertion portion, the orifice insertion portion being configured for insertion into an orifice of a patient during a magnetic resonance imaging guided biopsy;
a neck portion that connects the orifice insertion portion; and
a handle portion that connects to the neck portion;
wherein a cross-section diameter of the neck portion is smaller than a cross-section diameter of the orifice insertion portion, to provide additional patient comfort when the orifice insertion portion is inserted entirely within the orifice of the patient;
a needle tube that accommodates a needle of an intervention tool; and
an intervention tool securement and adjustment mechanism that controls a location of the intervention tool securement and adjustment mechanism on the neck portion, and controls an angle of the needle tube relative to the neck portion;
wherein the securement and adjustment mechanism includes a saddle situated on an exterior surface of the neck portion, the saddle being configured to be selectively movable along the neck portion to adjust and secure the location of the intervention tool securement and adjustment mechanism on the neck portion at any of a variety of selectable locations along the neck portion, and
wherein the securement and adjustment mechanism includes an angle adjustment mechanism that is configured to be selectively movable along the saddle to adjust and secure the angle of the needle tube at any of a variety of selectable angles relative to the neck portion.
2. The apparatus of claim 1 , wherein the orifice insertion portion includes an imaging coil configured for use with magnetic resonance imaging (MRI) of a tissue of interest in the patient.
3. The apparatus of claim 2 , wherein the MRI of the tissue of interest provides guidance of the intervention tool to the tissue of interest.
4. The apparatus of claim 1 , wherein the angle adjustment mechanism includes a locking mechanism to maintain the angle of insertion of the intervention tool.
5. The apparatus of claim 4 , wherein the orifice insertion portion of the probe includes a longitudinal axis and a channel therethrough, and the angle adjustment mechanism directs the intervention tool through the channel towards the tissue of interest.
6. The apparatus of claim 5 , further comprising a rotational adjustment mechanism removably attached to the probe and operable to rotate the probe around the longitudinal axis, whereby the angle adjustment mechanism is also rotated around the longitudinal axis.
7. The apparatus of claim 6 , wherein the intervention tool securement and adjustment mechanism, the rotational adjustment mechanism and the channel of the orifice insertion portion are configured so that, when the orifice insertion portion of the probe is inserted through the anus of the patient and positioned in the rectum, the intervention tool is delivered through the channel inter-orifice through the wall of the rectum to the tissue of interest.
8. The apparatus of claim 1 , wherein the orifice insertion portion and the neck portion are substantially cylindrical.
9. The apparatus of claim 1 , wherein the intervention tool securement and adjustment mechanism includes an intervention tool locking mechanism thereon, to secure the intervention tool in a desired location on the neck portion.
10. The apparatus of claim 9 , wherein the intervention tool securement and adjustment mechanism is configured so that, when the orifice insertion portion of the probe is inserted through the anus of the patient, the intervention tool is delivered transperineally to the tissue of interest.
11. The apparatus of claim 10 , wherein the intervention tool securement and adjustment mechanism further comprises a second imaging coil configured for use with MRI of the tissue of interest in the patient.
12. The apparatus of claim 10 , wherein the angle adjustment mechanism is removably attached to the intervention tool securement and adjustment mechanism.
13. The apparatus of claim 1 , wherein the securement and adjustment mechanism includes a slider that is configured to be selectively movable along the saddle to adjust the angle of the needle tube.
14. The apparatus of claim 1 , wherein the orifice insertion portion comprises a generally non-rigid exterior structure.
15. The apparatus of claim 1 , wherein the smaller cross-section diameter of the neck portion enables the patient's orifice to close around the neck portion to provide additional securement of the apparatus when in use.
16. The apparatus of claim 1 , wherein at least a section of the neck portion adjacent the orifice insertion portion is not covered by the intervention tool securement adjustment mechanism, thereby exposing the smaller cross-section diameter of the neck portion adjacent the orifice insertion portion.