IP Library › Granted Patent US 7,696,327
Granted Patent B1
US 7,696,327 · App. 09/202,054 · Granted Apr 13, 2010

Antibodies to human Toll homologues

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Quick Facts
Patent No.
US 7,696,327
App. No.
09/202,054
Granted
Apr 13, 2010
Kind
B1
Abstract

The invention relates to the identification and isolation of DNAs encoding the human Toll proteins PR0285, PR0286, and PR0358, and to methods and means for the recombinant production of these proteins. The invention also concerns antibodies specifically binding the PR0285, or PR0286, or PR0358 Toll protein.

Claims (6)

1. An isolated antibody which binds to a PRO285 polypeptide comprising:

(a) amino acids 1 to 1049 encoded by SEQ ID NO:2, or

(b) amino acid residues 20 to 836 of SEQ ID NO:1;

wherein the antibody is an agonist or an antagonist of NF-κB activation.

2. The antibody of claim 1 , wherein the antibody is an agonist of NF-κB activation.

3. The antibody of claim 1 , wherein the antibody is an antagonist of NF-κB activation.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 28, 2000
From: GODDARD, AUDREY; GODOWSKI, PAUL J.; GURNEY, AUSTIN L.; MARK, MELANIE R.; YANG, RUEY-BING
To: GENENTECH, INC.
Reel/Frame 011017/0186 →