Tropoelastin derivatives
View Patent ↗The disclosure relates to derivatives of tropoelastin and variants of those derivatives. The disclosure further provides expression products and hybrid molecules of the derivatives and variants of the invention. Methods for the production of the derivatives, variants, expression products and hybrid molecules are described. Formulations, cross-linked structures and implants comprising the derivatives, variants, expression products and hybrid molecules of the invention are included. Uses of the derivatives, variants, expression products and hybrid molecules are further provided.
1. An isolated tropoelastin derivative consisting of an amino acid sequence selected from the group consisting of SEQ ID NO:12 and SEQ ID NO:13.
2. An expression product consisting of the tropoelastin derivative of claim 1 and an amino acid sequence that is glutathione-S-transferase as a fusion protein.