Dietary control of arachidonic acid metabolism
Compositions for the treatment of symptoms of inflammatory disorders may include gamma-linolenic acid or dihomogammalinolenic acid, an inhibitor of Δ 5 desaturase, and optionally stearidonic acid or ω-3 arachidonic acid. Preferred formulations may be in the form of a good tasting, preferably milk or fruit based drink, or a dried powder. Compositions reduce inflammation and inhibit increase in serum arachidonic acid associated with gamma-linolenic acid.
1. A liquid dietary supplement consisting essentially of:
19.29 weight percent water;
25 weight percent sucrose;
35 weight percent oils;
15 weight percent flavoring;
5 weight percent glycerin; and
less than 1 weight percent minor ingredients selected from antioxidants, preservatives, colorants, stabilizers, emulsifiers or a combination thereof; wherein the oils are (i) concentrated borage oil and (ii) concentrated marine oil that contains eicosapentaenic acid.
2. The dietary supplement of claim 1 , wherein the oils consist of 57% concentrated borage oil and 43% concentrated marine oil.
3. The dietary supplement of claim 1 , wherein the flavoring is orange/peach flavor.
4. The dietary supplement of claim 1 , wherein the stabilizer is xanthan gum, the preservative is sorbic acid and the antioxidant is ascorbyl palmitate.