IP Library › Granted Patent US 7,226,992
Granted Patent B1
US 7,226,992 · App. 09/716,395 · Granted Jun 5, 2007

Mutant Bcl-2 proteins and uses thereof

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Quick Facts
Patent No.
US 7,226,992
App. No.
09/716,395
Granted
Jun 5, 2007
Kind
B1
Abstract

Mutant peptides derived from wild-type human Bcl-2 are disclosed. Assays to identify substances which block the ability of Bcl-2 to inhibit apoptosis also are disclosed.

Claims (2)

1. A mutant protein having an amino acid sequence comprising:

MAHAGRTGYDNREIVMKYIHYKLSQRGYEWDAGDDVEENRTEAPEGTESEVV HLALRQAGDDFSRRYRGDFAEMSSQLHLTPFTARGRAFTVVEELFRDGVNWG RIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLRHLHTWIQDNGGWDAFV ELYGPSMR (SEQ ID NO: 2).

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 8, 2013
From: ABBOTT LABORATORIES
To: ABBVIE INC.
Reel/Frame 030167/0733 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 12, 2001
From: PETROS, ANDREW M.; YOON, HO SUP; NETTESHEIM, DAVID G.
To: ABBOTT LABORATORIES
Reel/Frame 011397/0111 →