IP Library Granted Patent US 6,864,274
Granted Patent B2
US 6,864,274 · App. 09/758,781 · Granted Mar 8, 2005

Allantoin-containing skin cream

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Quick Facts
Patent No.
US 6,864,274
App. No.
09/758,781
Granted
Mar 8, 2005
Kind
B2
Abstract

An allantoin-containing skin cream composition can comprise allantoin and at least one anionic or nonionic emulsifier that is substantially hydrophilic and is soluble in water. The pH of the composition is in a range of from about 3.0 to about 6.0; preferably, the pH of the composition is from about 5.0 to about 6.0. The composition can further comprise an acidic anionic polymer. A preferred acidic anionic polymer is a carboxypolymethylene polymer. The composition can further comprise a carbohydrate polymer such as galactoarabinan, polygalactose or polyarabinose. The composition can additionally comprise other ingredients such as herbal extracts, an antioxidant component, an emollient component, a chelator, a solvent component, or a preservative component. The composition is useful as a skin protectant.

Claims (54)

1. A composition comprising an oil-in water emulsion comprising:

(a) allantoin;

(b) an emulsifier system comprising:

(i) sodium stearoyl lactylate;

(ii) sodium isostearoyl lactylate;

(iii) optionally, triethanolamine;

(iv) optionally, at least one nonionic emulsifier selected from the group consisting of a nonionic emulsifier that is an ethoxylated ether or an ethoxylated ester whose carbon chain length ranges from 8 to 22 carbon atoms; and

(c) an acid to adjust the pH to a range of from about 5.0 to about 5.8;

wherein the composition is stable and effective over the pH range; and

wherein the composition includes:

(a) from about 50.0% to about 90.0% of water;

(b) from about 2.0% to about 9.0% of propylene glycol;

(c) from about 0.05% to about 0.5% of citric acid;

(d) from about 0.30% to about 3.0% of sodium stearoyl lactylate;

(e) from about 0.05% to about 1.0% of sodium isostearoyl lactylate;

(f) from about 0.05% to about 0.25% of tetrasodium EDTA;

(g) from about 5.0% to about 15.0% of lanolin oil;

(h) from about 1.0% to about 8.0% of cetyl alcohol;

(i) from about 1.0% to about 7.0% of cod liver oil;

(j) from about 0.10% to about 1.0% of butylated hydroxytoluene;

(k) from about 0.10% to about 0.50% of methylparaben;

(l) from about 0.10% to about 0.50% of propylparaben;

(m) from about 0.50% to about 2.0% of allantoin; and

(n) from about 0.05% to about 0.50% of fragrance.

2. The composition of claim 1 where the composition comprises:

(a) from about 60.0% to about 80.0% of water;

(b) from about 4.0% to about 7.0% of propylene glycol;

(c) from about 0.10% to about 0.40% of citric acid;

(d) from about 0.50% to about 2.5% of sodium stearoyl lactylate;

(e) from about 0.10% to about 0.70% of sodium isostearoyl lactylate;

(f) from about 0.10% to about 0.20% of tetrasodium EDTA;

(g) from about 8.0% to about 12.0% of lanolin oil;

(h) from about 2.0% to about 7.0% of cetyl alcohol;

(i) from about 1.0% to about 4.0% of cod liver oil;

(j) from about 0.20% to about 0.80% of butylated hydroxytoluene;

(k) from about 0.15% to about 0.40% of methylparaben;

(l) from about 0.15% to about 0.40% of propylparaben;

(m) from about 1.0% to about 2.0% of allantoin; and

(n) from about 0.10% to about 0.40% of fragrance.

3. The composition of claim 2 where the composition comprises:

(a) about 73.42% of water;

(b) about 5.70% of propylene glycol;

(c) about 0.18% of citric acid;

(d) about 1.00% of sodium stearoyl lactylate;

(e) about 0.25% of sodium isostearoyl lactylate;

(f) about 0.15% of tetrasodium EDTA;

(g) about 15.0% of lanolin oil;

(h) about 3.80% of cetyl alcohol;

(i) about 2.00% of cod liver oil;

(j) about 0.50% of butylated hydroxytoluene;

(k) about 0.30% of methylparaben;

(l) about 0.25% of propylparaben;

(m) about 1.50% of allantoin; and

(n) about 0.20% of fragrance.

Assignments (3)
SECURITY INTEREST Recorded Oct 6, 2023
From: AMICUS THERAPEUTICS, INC.
To: WILMINGTON TRUST, NATIONAL ASSOCIATION
Reel/Frame 065177/0196 →
RELEASE OF SECURITY INTEREST Recorded Sep 16, 2015
From: SWEEN, MAURICE A.
To: ALWYN COMPANY, INC.
Reel/Frame 036580/0525 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 31, 2013
From: ALWYN COMPANY, INC.
To: SCIODERM, INC.
Reel/Frame 030914/0460 →