IP Library Granted Patent US 6,960,173
Granted Patent B2
US 6,960,173 · App. 09/774,145 · Granted Nov 1, 2005

Ultrasound wound treatment method and device using standing waves

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Quick Facts
Patent No.
US 6,960,173
App. No.
09/774,145
Granted
Nov 1, 2005
Kind
B2
Abstract

The method and device of the present invention for wound treatment with ultrasound standing waves includes a transducer probe to produce ultrasonic waves. The ultrasonic transducer has a tip with a distal radiation surface that radiates ultrasound energy toward the surface of a wound. Ultrasound standing waves occurring as a result of incident and reflected waves from the wound surface create ultrasonic radiation pressure. Ultrasound radiation pressure increases the blood flow in wound area, and ultrasound waves kill bacteria, stimulate healthy tissue cell and treat wounds.

Claims (22)

1. A method for treating an external wound from a non-contact distance d, comprising the steps of:

positioning an ultrasound transducer such that a distal radiation surface of the ultrasound transducer is positioned at a distance substantially equal to the non-contact distance d from the surface of the external wound; and

creating and maintaining ultrasound standing waves between the surface of the external wound and the distal radiation surface, wherein the ultrasound standing waves are created and maintained in air along the non-contact distance d, wherein the non-contact distance d is determined by the formula:

d=n ×λ/2,

where λ is the wavelength of an ultrasound standing wave and n is a positive integer, and wherein the ultrasound standing waves create radiation pressure for providing a bactericidal and a therapeutic effect to the external wound for decreasing the healing time for the external wound.

2. The method of claim 1 , wherein the ultrasound transducer operates at a frequency of from about 10 kHz to 10 3 MHz.

3. The method of claim 1 , wherein the non-contact distance d is at least 0.1 inch.

4. The method of claim 1 , wherein in a prior step a gel or drug is applied to the wound surface.

5. A method for treating an external wound from a non-contact distance comprising the steps of:

providing a transducer having a distal radiation surface arranged at the non-contact distance from the surface of the external wound for emitting ultrasonic waves; and

creating and maintaining ultrasound standing waves in air between the surface of the external wound and the distal radiation surface by adjusting the non-contact distance, wherein the ultrasound standing waves create radiation pressure for providing a bactericidal and a therapeutic effect to the external wound for decreasing the healing time for the external wound.

6. The method of claim 5 , wherein the transducer operates at a frequency from 10 kHz to 10,000 MHz.

7. The method of claim 5 , wherein the non-contact distance is at least 0.1 inch.

8. The method of claim 5 , further comprising the steps of:

driving the transducer by pulsed or modulated frequency; and

selecting the driving wave form of the transducer from the group consisting of sinusoidal, rectangular, trapezoidal and triangular wave forms.

9. The method of claim 5 , wherein the therapeutic effect is selected from the group consisting of increasing blood flow to the external wound, mechanically cleansing the external wound, dissolving blood clots within a vessel exposed as an external wound, diffusing grafts, stimulating cell growth, providing at least one medicament to the external wound, and penetrating at least one medicament through the surface of the external wound.

10. The method of claim 5 , further comprising the steps of:

applying a drug to the external wound; and

penetrating the drug through the surface of the external wound using the radiation pressure created by the ultrasound standing waves.

11. The method of claim 5 , further comprising the step of providing a bushing around the distal radiation surface for increasing the radiation pressure created by the ultrasound standing waves, wherein the non-contact distance is between a distal end of the bushing and the surface of the external wound.

12. The method of claim 5 , further comprising the step of focusing the ultrasound waves.

Assignments (12)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 6, 2020
From: CELULARITY INC.
To: SANUWAVE HEALTH, INC.
Reel/Frame 054299/0846 →
SECURITY INTEREST Recorded Aug 7, 2020
From: SANUWAVE HEALTH, INC.
To: NH EXPANSION CREDIT FUND HOLDINGS LP
Reel/Frame 053435/0842 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 8, 2020
From: ALLIQUA BIOMEDICAL, INC.
To: CELULARITY INC.
Reel/Frame 053152/0144 →
RELEASE OF SECURITY INTEREST Recorded May 9, 2018
From: PERCEPTIVE CREDIT OPPORTUNITIES FUND, LP C/O PERCEPTIVE ADVISORS LLC
To: ALQA CEDAR, INC.
Reel/Frame 045756/0204 →
CHANGE OF ASSIGNEE ADDRESS Recorded Mar 28, 2016
From: CELLERATION, INC.
To: ALLIQUA BIOMEDICAL, INC.
Reel/Frame 038274/0778 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 21, 2015
From: CELLERATION, INC.
To: ALLIQUA BIOMEDICAL, INC.
Reel/Frame 036140/0913 →
SECURITY INTEREST Recorded May 29, 2015
From: ALQA CEDAR, INC.
To: PERCEPTIVE CREDIT OPPORTUNITIES FUND, LP C/O PERCEPTIVE ADVISORS LLC
Reel/Frame 035745/0313 →
RELEASE OF SECURITY INTEREST Recorded Sep 23, 2008
From: GE TECHNOLOGY FINANCE CORPORATION
To: CELLERATION, INC.
Reel/Frame 021561/0802 →
MERGER Recorded Mar 30, 2007
From: CELLERATION, INC.
To: CELLERATION, INC.
Reel/Frame 019094/0591 →
CHANGE OF NAME Recorded Mar 30, 2007
From: ADVANCED MEDICAL APPLICATIONS, INC.
To: CELLERATION, INC.
Reel/Frame 019102/0655 →
SECURITY INTEREST Recorded Apr 7, 2003
From: CELLERATION, INC.
To: TRANSAMERICA TECHNOLOGY FINANCE CORPORATION
Reel/Frame 013907/0846 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 31, 2001
From: BABAEV, EILAZ
To: ADVANCED MEDICAL APPLICATIONS, INC.
Reel/Frame 012410/0604 →
Continuity (1)
Related Publication 20020103448A1 · Aug 1, 2002