Rapidly disintegrable solid preparation
View Patent ↗A rapidly disintegrable solid preparation which comprises (i) a pharmacologically active ingredient, (ii) a sugar and (iii) a low-substituted hydroxypropylcellulose having 5% by weight or more to less than 7% by weight of hydroxypropoxyl group. The rapidly disintegrable solid preparation has fast disintegrability, suitable strength and no roughness.
1. An oral rapidly disintegrable solid preparation which comprises (i) manidipine hydrochloride, (ii) a sugar and (iii) a low-substituted hydroxypropylcellulose having 5% by weight or more to less than 7% by weight of hydroxypropoxyl groups; wherein said solid preparation is buccally dissolved in from about 5 to about 50 seconds.
2. An oral rapidly disintegrable solid preparation which comprises (i) pioglitazone hydrochloride, (ii) a sugar and (iii) a low-substituted hydroxypropylcellulose having 5% by weight or more to less than 7% by weight of hydroxypropoxyl groups; wherein said solid preparation is buccally dissolved in from about 5 to about 50 seconds.