IP Library › Granted Patent US 7,550,573
Granted Patent B2
US 7,550,573 · App. 09/944,929 · Granted Jun 23, 2009

Secreted and transmembrane polypeptides and nucleic acids encoding the same

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Quick Facts
Patent No.
US 7,550,573
App. No.
09/944,929
Granted
Jun 23, 2009
Kind
B2
Abstract

The present invention is directed to secreted and transmembrane polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

Claims (19)

1. An isolated nucleic acid comprising:

(a) a nucleic acid sequence encoding the polypeptide shown in FIG. 32 (SEQ ID NO: 83);

(b) a nucleic acid sequence encoding the polypeptide shown in FIG. 32 (SEQ ID NO: 83), lacking its associated signal peptide;

(c) a nucleic acid sequence encoding the extracellular domain of the polypeptide shown in FIG. 32 (SEQ ID NO: 83);

(d) a nucleic acid sequence encoding the extracellular domain of the polypeptide shown in FIG. 32 (SEQ ID NO: 83), lacking its associated signal peptide;

(e) the nucleic acid sequence shown in FIG. 31 (SEQ ID NO: 82);

(f) the full-length coding sequence of the nucleic acid sequence shown in FIG. 31 (SEQ ID NO: 82); or

(g) the full-length-coding sequence of the cDNA deposited under ATCC accession number 209621.

2. The isolated nucleic acid of claim 1 comprising a nucleic acid sequence encoding the polypeptide shown in FIG. 32 (SEQ ID NO: 83).

3. The isolated nucleic acid of claim 1 comprising a nucleic acid sequence encoding the polypeptide shown in FIG. 32 (SEQ ID NO: 83), lacking its associated signal peptide.

4. The isolated nucleic acid of claim 1 comprising a nucleic acid sequence encoding the extracellular domain of the polypeptide shown in FIG. 32 (SEQ ID NO: 83).

5. The isolated nucleic acid of claim 1 comprising a nucleic acid sequence encoding the extracellular domain of the polypeptide shown in FIG. 32 (SEQ ID NO: 83), lacking its associated signal peptide.

6. The isolated nucleic acid sequence of claim 1 comprising the nucleic acid sequence shown in FIG. 31 (SEQ ID NO: 82).

7. The isolated nucleic acid sequence of claim 1 comprising the full-length coding sequence of the nucleic acid sequence shown in FIG. 31 (SEQ ID NO: 82).

8. The isolated nucleic acid sequence of claim 1 comprising the full-length coding sequence of the cDNA deposited under ATCC accession number 209621.

9. A vector comprising the nucleic acid of claim 1 .

10. The vector of claim 9 , wherein said nucleic acid is operably linked to control sequences recognized by a host cell transformed with the vector.

11. A host cell comprising the vector of claim 9 .

12. The host cell of claim 11 , wherein said cell is a CHO cell, an E. coli or a yeast cell.