IP Library › Granted Patent US 6,929,947
Granted Patent B2
US 6,929,947 · App. 09/944,944 · Granted Aug 16, 2005

Secreted and transmembrane polypeptides and nucleic acids encoding the same

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Quick Facts
Patent No.
US 6,929,947
App. No.
09/944,944
Granted
Aug 16, 2005
Kind
B2
Abstract

The present invention is directed to nucleic acids encoding a secreted polypeptide that inhibits neoplastic growth in tumor cells. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

Claims (5)

1. An isolated nucleic acid comprising the nucleic acid sequence shown in FIG. 17 (SEQ ID NO:41).

2. A vector comprising the nucleic acid of claim 1 .

3. The vector of claim 2 , wherein said nucleic acid is operably linked to control sequences recognized by a host cell transformed with the vector.

4. A host cell comprising the vector of claim 2 .

5. The host cell of claim 4 , wherein said cell is a CHO cell, an E. coli or a yeast cell.