IP Library Granted Patent US 7,201,896
Granted Patent B1
US 7,201,896 · App. 09/980,823 · Granted Apr 10, 2007

IL6RIL6 chimera for the treatment of neurodegenerative diseases

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Quick Facts
Patent No.
US 7,201,896
App. No.
09/980,823
Granted
Apr 10, 2007
Kind
B1
Abstract

The invention relates to the use of IL6RIL6 chimera in the treatment and prevention of neurological diseases and disorders.

Claims (5)

1. A method for inducing myelination and remyelination of neurons, comprising administering to a patient in need thereof an effective amount of interleukin-6 receptor

interleukin-6 (IL6RIL6) chimera, thereby resulting in the induction of myelination or remyelination of neurons.

2. The method of claim 1 , for inducing myelination and remyelination of neurons, wherein the patient in need is one suffering from traumatic nerve degeneration or a demyelinating disease of the central nervous system (CNS) or peripheral nervous system (PNS).

3. The method of claim 1 , wherein the patient in need is one suffering from multiple sclerosis (MS).

4. A method in accordance with claim 1 , wherein said IL6RIL6 chimera is administered together with a pharmaceutically acceptable carrier.

Assignments (5)
CHANGE OF NAME Recorded Nov 25, 2009
From: LABORATOIRES SERONO SA
To: MERCK SERONO SA
Reel/Frame 023569/0120 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 11, 2007
From: APPLIED RESEARCH SYSTEMS ARS HOLDING N.V.
To: LABORATOIRES SERONO SA
Reel/Frame 019966/0026 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 6, 2007
From: PIZZI, MARINA; SPANO, PIERFRANCO
To: APPLIED RESEARCH SYSTEMS ARS HOLDING N.V.
Reel/Frame 019125/0902 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 18, 2007
From: BOSCHERT, URSULA
To: APPLIED RESEARCH SYSTEMS ARS HOLDING N.V
Reel/Frame 018768/0897 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 18, 2007
From: REVEL, MICHEL; CHEBATH, JUDITH
To: YEDA RESEARCH AND DEVELOPMENT CO. LTD.
Reel/Frame 018770/0125 →