IP Library Granted Patent US 7,013,173
Granted Patent B2
US 7,013,173 · App. 09/997,872 · Granted Mar 14, 2006

Optical probe with reference fiber

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Quick Facts
Patent No.
US 7,013,173
App. No.
09/997,872
Granted
Mar 14, 2006
Kind
B2
Abstract

A system for characterizing tissue includes the steps of generating an emission signal, generating a reference signal, directing the emission signal to and from the tissue, directing the reference signal in a predetermined manner relative to the emission signal, and using the reference signal to compensate the emission signal. In one embodiment compensation is provided for fluctuations in light delivery to the tip of the probe due to cable motion.

Claims (11)

1. A system for producing a signal adapted to characterize tissue and to correct for optical fluctuations, consisting of:

a laser module for generating an emission signal and a reference signal,

a splitter connected to said laser module for splitting said emission signal and said reference signal,

a probe with a needle that is adapted to be inserted into the tissue and that directs said emission signal to the probe and through the needle to the tissue for characterizing the tissue,

an emission optical detector,

a reference optical detector,

a transmission system including

an emission optical fiber connected to said said splitter, to said probe, to said needle, and to said emission optical detector that transmits said emission signal to said probe, to said needle, and from said probe to the tissue for characterizing the tissue, and from the tissue to said needle, to said probe and to said emission optical detector, and

a reference optical fiber connected to said said splitter, to said probe, and to said reference optical detector that transmits said reference signal to said probe and from said probe to said reference optical detector, and

a compensation system that utilizes said reference signal to correct said emission signal and producing a signal for characterizing the tissue for the optical fluctuations.

2. The system for producing a signal adapted to characterize tissue of claim 1 , wherein said laser module comprises multiple lasers that generate said optical emission signal and said optical reference signal.

Assignments (4)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 23, 2008
From: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
To: LAWRENCE LIVERMORE NATIONAL SECURITY LLC
Reel/Frame 021217/0050 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 15, 2006
From: CHASE, CHARLES L.
To: BIOLUMINATE, INC.
Reel/Frame 017794/0193 →
CONFIRMATORY LICENSE Recorded Oct 7, 2002
From: CALIFORNIA, UNIVERSITY OF
To: ENERGY, U.S. DEPARTMENT OF
Reel/Frame 013391/0795 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 29, 2001
From: DA SILVA, LUIZ B.
To: REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE
Reel/Frame 012345/0590 →