IP Library Granted Patent US 6,986,893
Granted Patent B2
US 6,986,893 · App. 10/008,722 · Granted Jan 17, 2006

Method for treating a mucus secretion

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Quick Facts
Patent No.
US 6,986,893
App. No.
10/008,722
Granted
Jan 17, 2006
Kind
B2
Abstract

A method and composition for treating a patient suffering from an excessive mucus secretion includes administration to the patient of a therapeutically effective amount of a botulinum toxin type A, B, C, D, E, F and/or G.

Claims (17)

1. A method for treating a mucus secretion of a patient, the method comprising the step of administering an effective amount of a botulinum toxin to a region of a patient selected from the group consisting of the gastrointestinal tract and the genital tract in order to reduce a mucus secretion of the patient, wherein the mucus secretion is not a symptom of rhinorrhea.

2. The method of claim 1 , wherein the mucus secretion is a cholinergic influenced mucus secretion.

3. The method of claim 1 , wherein the botulinum toxin is botulinum toxin type A.

4. The method of claim 1 , wherein the botulinum toxin is selected from the group consisting of botulinum toxin types A, B, C, D, E, F and G.

5. The method of claim 1 , wherein the botulinum toxin is administered in an amount of between 0.01 units and 5000 units.

6. The method of claim 1 , wherein the botulinum toxin is administered in an amount of between 0.01 unit and 500 units.

7. A method for treating a cholinergic influenced mucus secretion of a human patient, the method comprising the step of administering a therapeutically effective amount of botulinum toxin type A to a region of a patient selected from the group consisting of the gastrointestinal tract and the genital tract in order to reduce the mucus secretion, wherein the mucus secretion is not a symptom of rhinorrhea.

8. A method for treating a mucus secreting gland, the method comprising the step of administering to a mucus secreting gland of a region selected from the group consisting of the gastrointestinal tract, the genital tract, and the respiratory tract of a patient a botulinum toxin thereby reducing a mucus secretory activity of the gland, wherein the mucus secretion is not a symptom of rhinorrhea.

9. The method of claim 8 , wherein the gland is an excessively secreting mucus gland.

10. The method of claim 8 , wherein the mucus gland is influenced by the cholinergic nervous system.

11. The method of claim 8 , wherein the botulinum toxin is administered by injection into the mucus gland or into the local area of the mucus gland.

12. The method of claim 8 , wherein the botulinum toxin is botulinum toxin type A.

13. The method of claim 8 , wherein the botulinum toxin is selected from the group consisting of botulinum toxin types A, B, C, D, E, F and G.

14. The method of claim 8 , wherein the botulinum toxin is administered in an amount of between 0.01 units and 5000 units.

15. The method of claim 8 , wherein the botulinum toxin is administered in an amount of between 0.01 units and 500 units.

16. A method for treating an excessively secreting mucus gland, the method comprising the step of injecting an excessively secreting, cholinergic nervous system influenced mucus gland or local mucus gland area of a region selected from the group consisting of the gastrointestinal tract, the genital tract, and the respiratory tract of a human patient with a therapeutically effective amount of botulinum toxin type A in order to reduce the excessive mucus gland secretion, wherein the mucus secretion is not a symptom of rhinorrhea.

17. The method of claim 1 , wherein the botulinum toxin is administered into a hyperactive intestinal mucosa.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 7, 2003
From: ALLERGAN SALES, INC. (MERGED INTO ALLERGAN SALES, LLC 6/3/2002)
To: ALLERGAN, INC.
Reel/Frame 013898/0170 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 22, 2002
From: AOKI, KEI ROGER; GRAYSTON, MICHAEL W.
To: ALLERGAN SALES, INC.
Reel/Frame 012915/0585 →