Compositions normalizing circadian rhythm
View Patent ↗The present invention provides a circadian rhythm normalizing composition containing astaxanthin and/or its ester as an active ingredient, and a composition having the action of enhancing the circadian rhythm normalizing action of melatonin by protecting melatonin. The composition can be in the form of a drug, a functional food, a food or a beverage. This composition has a circadian rhythm normalizing action, and has the action of preventing or alleviating sleep disorder and various diseases due to disturbance of the circadian rhythm.
1. A method of normalizing circadian rhythm by administering to a patient suffering from disturbance of circadian rhythm, an effective amount of astaxanthin and/or an ester thereof, and an effective amount of melatonin.
2. The method of claim 1 wherein said effective amount of astaxanthin and/or an ester thereof ranges from 0.5–500 mg/day.
3. The method of claim 1 wherein said effective amount of astaxanthin and/or an ester thereof ranges from 5–50 mg/day.