Biologically active composites and methods for their production and use
View Patent ↗Biologically active composites containing calcium phosphate, more specifically beta-tri-calcium phosphate, and methods of preparing the same are disclosed herein. Also disclosed are methods of restoring an osseous void and complimentary kits for the disclosed composites.
1. A method for restoring an intraosseous void comprising:
preparing said void;
providing an aspirating means having porous, biocompatible material having macro-, meso-, and microporosity therein;
aspirating bone marrow from an animal using said aspirating means;
saturating said porous material with said bone marrow aspirate;
allowing said aspirate to at least partially coagulate;
removing said composite from the aspirating means; and
placing at least a portion of said composite into said void.
2. The method of claim 1 wherein said composite is shaped to fit said void prior to insertion into said void.
3. The method of claim 1 wherein said aspirating means is a syringe.
4. The method of claim 3 wherein resultant composite is delivered into said void by syringe.
5. The method of claim 1 wherein the aspirate is allowed to coagulate for at least five minutes.
6. The method of claim 1 further comprising preserving any remaining resultant composite for later use.
7. The method of claim 1 wherein preservation is by freezing.
8. The method of claim 1 wherein the porous material is comprised of a resorbable beta-tri-calcium phosphate with interconnected micro, meso and macro pores that render said porous biocompatible material at least about 90% porous.