Granted Patent
B2
US 6,872,734 · App. 10/041,782 · Granted Mar 29, 2005
Use of tiagabine for treatment of diabetic neuropathy and migraine
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Abstract
(R)-N-[4,4-Bis(3-methyl-2-thienyl)-3-butenyl]nipecotic acid and salts thereof are effective GABA uptake inhibitory compounds and exert pharmacological effects on pain associated with diabetic neuropathy and migraine.
Claims (2)
1. A method of treating pain associated with diabetic polyneuropathy in a patient in need thereof by administering a pharaceutically effective amount of the compound (R)-N-[4,4Bis(3-methyl-2-thienyl)-3-butenyl]nipecotic acid hydrochloride to said patient.
2. The method of claim 1 wherein said (R)-N-[4,4-Bis(3-methyl-2-thienyl)-3butenyl]nipecotic acid hydrochloride is in an extended release formulation.
Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Apr 8, 2013
From: ABBOTT LABORATORIES
To: ABBVIE INC.
Reel/Frame 030167/0733 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Mar 25, 2002
From: COLLINS, STEPHEN D.; DEATON, ROGER L.; GIARDINA, WILLIAM J.; GILBERT, ADRIENNE L.
To: ABBOTT LABORATORIES
Reel/Frame 012516/0663 →