IP Library › Granted Patent US 6,930,168
Granted Patent B2
US 6,930,168 · App. 10/056,583 · Granted Aug 16, 2005

Synthetic peptides for demyelinating conditions

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Quick Facts
Patent No.
US 6,930,168
App. No.
10/056,583
Granted
Aug 16, 2005
Kind
B2
Abstract

The invention provides peptide compositions and methods of making and using therapeutic compositions comprising peptides for the treatment of a subject having a demyelinating condition.

Claims (31)

1. A composition comprising a synthetic peptide having an amino acid sequence selected from the group consisting of:

EAAKYEAYKAAAAAA,

(SEQ ID NO: 64)

EKAKYEAYKAAAAAA,

(SEQ ID NO: 65)

EAKKYEAYKAAAAAA,

(SEQ ID NO: 66)

EAPKYEAYKAAAAPA,

(SEQ ID NO: 84)

EAPKYEAYKAAAAPA,

(SEQ ID NO: 86)

APEKAKYEAYKAAAAAA,

(SEQ ID NO: 88)

APEKAKYEAYKAAAAAAPA,

(SEQ ID NO: 89)

EKAKYEAYKAAAAAAPA,

(SEQ ID NO: 90)

EKPKFEAYKAAAAPA,

(SEQ ID NO: 91)

EKPKVEAYKAAAAPA,

(SEQ ID NO: 93)

EKAKFEAFKAAAAAA,

(SEQ ID NO: 95)

APEKAKFEAEKAAAAPA,

(SEQ ID NO: 96)

and

APEKAKFEAYKAAAAPA,

(SEQ ID NO: 97).

2. The composition of claim 1 , wherein the peptide is substantially pure.

3. The composition of claim 1 , wherein the peptide comprises an oligomer having a plurality of monomer units having the amino acid sequence of the synthetic peptide, the units joined by a flexible linker.

4. A kit comprising at least one container having a peptide as shown in claim 1 , in a pharmaceutically acceptable buffer, and instructions for use.

Assignments (1)
CONFIRMATORY LICENSE Recorded Dec 31, 2008
From: HARVARD UNIVERSITY
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 022044/0196 →