IP Library Granted Patent US 7,031,776
Granted Patent B2
US 7,031,776 · App. 10/056,793 · Granted Apr 18, 2006

Methods for improving damaged retinal cell function

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Quick Facts
Patent No.
US 7,031,776
App. No.
10/056,793
Granted
Apr 18, 2006
Kind
B2
Abstract

Methods of using electrical stimulation by itself or in conjunction with growth factors to treat and prevent visual loss due to choroidal, retinal pigment epithelial and/or neuroretinal cell degeneration and dysfunction are presented.

Claims (10)

1. A method of improving visual function of a damaged retina in a human eye, the method comprising:

applying electrical stimulation to the eye with a source of electrical stimulation to improve visual function of the damaged retina, wherein applying electrical stimulation improves visual function of at least one structure of the damaged retina not in contact with the source of electrical stimulation, and wherein the electrical stimulation comprises a voltage potential, V p , of −20V≦V p ≦+20V.

2. The method of claim 1 , wherein the V p is −5V≦V p ≦+5V.

3. The method of claim 1 , wherein the V p is −1V≦V p ≦+1V.

4. The method of claim 1 , wherein said electrical stimulation is intermittent.

5. A method of treating visual degradation resulting from a damaged retina, wherein the visual degradation comprises primary or secondary degradation, the method comprising:

applying electrical stimulation to an eye containing the damaged retina with a source of electrical stimulation, wherein a portion of the damaged retina not in contact with the source of electrical stimulation is treated, and wherein the electrical stimulation comprises a voltage potential, V p , of −20V≦V p ≦+20V.

6. The method of claim 5 , wherein the V p is −5V≦V p ≦+5V.

7. The method of claim 5 , wherein the V p is −1V≦V p ≦+1V.

8. The method of claim 5 , wherein the electrical stimulation is intermittent.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 25, 2013
From: IMI INTELLIGENT MEDICAL IMPLANTS AG
To: PIXIUM VISION SA
Reel/Frame 031719/0914 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 15, 2008
From: OPTOBIONICS CORPORATION
To: IMI INTELLIGENT MEDICAL IMPLANTS AG
Reel/Frame 020507/0679 →
SECURITY AGREEMENT Recorded Apr 23, 2007
From: OPTOBIONICS CORPORATION
To: ARCH VENTURE FUND III, L.P.; ARCH VENTURE FUND V, L.P.; ARCH V ENTREPRENEURS FUND, L.P.; POLARIS VENTURE PARTNERS, L.P.; POLARIS VENTURE PARTNERS FOUNDERS' FUND, L.P.; POLARIS VENTURE PARTNERS III, L.P.; POLARIS VENTURE PARTNERS ENTREPRENEURS' FUND III, L.P.; POLARIS VENTURE PARTNERS FOUNDERS' FUND III, L.P.; ADVANCED TECHNOLOGY VENTURES V, L.P.; ATV ENTREPRENEURS V, L.P.; MEDTRONIC INTERNATIONAL, LTD.; CHO, ALAN
Reel/Frame 019181/0882 →