IP Library › Granted Patent US 7,253,256
Granted Patent B2
US 7,253,256 · App. 10/063,549 · Granted Aug 7, 2007

Polypeptides encoded by a nucleic acid are expressed in esophageal and kidney tumor

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Quick Facts
Patent No.
US 7,253,256
App. No.
10/063,549
Granted
Aug 7, 2007
Kind
B2
Abstract

The present invention is directed to novel polypeptides encoded by nucleic acids that are differently expressed in esophageal and kidney tumors.

Claims (13)

1. An isolated polypeptide comprising:

(a) the amino acid sequence of the polypeptide of SEQ ID NO:46;

(b) the amino acid sequence of the polypeptide of SEQ ID NO:46, lacking its associated signal peptide, amino acids 1-22;

(c) the amino acid sequence of amino acids 23-223 of SEQ ID NO:46;

(d) the amino acid sequence of amino acids 23-223 of SEQ ID NO:46, including its associated signal peptide, amino acids 1-22; or

(e) the amino acid sequence of the polypeptide encoded by the full-length coding sequence of the cDNA deposited under ATCC accession number 209956.

2. The isolated polypeptide of claim 1 comprising the amino acid sequence of the polypeptide of SEQ ID NO:46.

3. The isolated polypeptide of claim 1 comprising the amino acid sequence of the polypeptide of SEQ ID NO:46, lacking its associated signal peptide, amino acids 1-22.

4. The isolated polypeptide of claim 1 comprising the amino acid sequence of amino acids 23-223 of SEQ ID NO:46.

5. The isolated polypeptide of claim 1 comprising the amino acid sequence of amino acids 23-223 of SEQ ID NO:46, including its associated signal peptide, amino acids 1-22.

6. The isolated polypeptide of claim 1 comprising the amino acid sequence of the polypeptide encoded by the full-length coding sequence of the cDNA deposited under ATCC accession number 209956.

7. A chimeric polypeptide comprising a polypeptide according to claim 1 fused to a heterologous polypeptide.

8. The chimeric polypeptide of claim 7 , wherein said heterologous polypeptide is a tag polypeptide or an Fc region of an immunoglobulin.