IP Library Granted Patent US 7,089,060
Granted Patent B1
US 7,089,060 · App. 10/080,642 · Granted Aug 8, 2006

Methods of stimulating cell receptor activity using electromagnetic fields

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Quick Facts
Patent No.
US 7,089,060
App. No.
10/080,642
Granted
Aug 8, 2006
Kind
B1
Abstract

A method for activating a vascular endothelial growth factor (VEGF) receptor of one or more cells includes positioning an electromagnetic field generator in proximity to a VEGF receptor such that the flux of an electromagnetic field generated by the electromagnetic field generator will extend through the VEGF receptor. The method also includes generating an electromagnetic field, using the electromagnetic field generator, having a rate of fluctuation that activates the VEGF receptor.

Claims (23)

1. A method for activating a vascular endothelial growth factor (VEGF) receptor of one or more cells, the method comprising:

positioning an electromagnetic field generator in proximity to a VEGF receptor such that the flux of an electromagnetic field generated by the electromagnetic field generator will extend through the VEGF receptor; and

generating an electromagnetic field burst using the electromagnetic field generator having a rate of fluctuation that activates the VEGF receptor,

wherein the electromagnetic field burst has a burst period of approximately 26 msec, and

wherein the rate of fluctuation is about 3831 Hertz or about 3861 Hertz.

2. The method of claim 1 , wherein the VEGF receptor is part of a human bone cell.

3. The method of claim 1 , wherein the VEGF receptor is part of a human vascular endothelial cell.

4. The method of claim 1 , wherein VEGF receptors of a plurality of cells are activated by the electromagnetic field.

5. The method of claim 1 , wherein the electromagnetic field is generated such that the electromagnetic field causes cell growth to occur that is substantially similar to cell growth that occurs when a VEGF receptor is activated by a VEGF ligand.

6. A method for activating a vascular endothelial growth factor (VEGF) receptor of one or more cells, the method comprising:

positioning an electromagnetic field generator in proximity to a VEGF receptor such that the flux of an electromagnetic field generated by the electromagnetic field generator will extend through the VEGF receptor; and

generating an electromagnetic field burst using the electromagnetic field generator having a rate of fluctuation that activates the VEGF receptor,

wherein the electromagnetic field burst has a burst period of approximately 5.5 msec, and

wherein the rate of fluctuation is about 3831 Hertz or about 3861 Hertz.

7. The method of claim 6 , wherein the VEGF receptor is part of a human bone cell.

8. The method of claim 6 , wherein the VEGF receptor is part of a human vascular endothelial cell.

9. The method of claim 6 , wherein VEGF receptors of a plurality of cells are activated by the electromagnetic field.

10. The method of claim 6 , wherein the electromagnetic field is generated such that the electromagnetic field causes cell growth to occur that is substantially similar to cell growth that occurs when a VEGF receptor is activated by a VEGF ligand.

11. A method for activating a vascular endothelial growth factor (VEGF) receptor of one or more cells, the method comprising:

positioning an electromagnetic field generator in proximity to a VEGF receptor such that the flux of an electromagnetic field generated by the electromagnetic field generator will extend through the VEGF receptor; and

generating an electromagnetic field burst using the electromagnetic field generator having a rate of fluctuation that activates the VEGF receptor,

wherein the electromagnetic field burst has a burst period of approximately 26 msec, and

wherein the rate of fluctuation is about 62 kHz to 63 kHz.

Assignments (3)
SECURITY INTEREST Recorded Oct 28, 2019
From: ORTHOFIX INC.
To: JPMORGAN CHASE BANK, N.A.
Reel/Frame 050839/0155 →
SECURITY INTEREST Recorded Sep 24, 2015
From: AMEI TECHNOLOGIES INC.
To: JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT
Reel/Frame 036649/0821 →
RELEASE OF SECURITY INTEREST Recorded Sep 24, 2015
From: JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT
To: AMEI TECHNOLOGIES, INC.; ORTHOFIX, INC.
Reel/Frame 036676/0232 →