Use of cytokine inhibitors
View Patent ↗The present invention relates to a method for prevention or reduction of scar tissue and/or adhesion formation wherein a therapeutically effective amount of a substance that inhibits a pro-inflammatory cytokine such as TNF or IL-1, is administered to a patient in need of said treatment.
1. A method for reduction of adhesion formation comprising administering a therapeutically effective amount of a substance that inhibits a pro-inflammatory cytokine to a patient in need thereof, wherein; the administration of the substance that inhibits a pro-inflammatory cytokine causes a reduction in adhesion formation, and wherein; said substance is the peptide of SEQ ID NO: 3 or SEQ ID NO: 37.
2. The method of claim 1 , for treatment of post-traumatic tissue injury.
3. The method of claim 1 , for treatment of a thermic injury.
4. The method of claim 1 , for treatment of a pathological condition with scar formation.
5. The method of claim 2 , wherein said post-traumatic tissue injury is caused by surgery.
6. The method of claim 4 , wherein said pathological condition with scar formation is caused by a vascular disease selected from the group consisting of bleeding and infarct.
7. The method of claim 4 , wherein said pathological condition with scar formation is caused by a toxic influence.
8. The method of claim 4 , wherein said pathological condition with scar formation is caused by cystic fibrosis.
9. The method of claim 1 , wherein said substance is locally administered.
10. The method of claim 1 , wherein said substance is systemically administered.