IP Library Granted Patent US 7,134,437
Granted Patent B2
US 7,134,437 · App. 10/104,250 · Granted Nov 14, 2006

Method for utilizing human tissue

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Quick Facts
Patent No.
US 7,134,437
App. No.
10/104,250
Granted
Nov 14, 2006
Kind
B2
Abstract

Percutaneous tissue removal apparatus comprises a flexible drill shaft, a cutting tip mounted on the shaft for placement adjacent a tissue mass for cutting the tissue, means for transmitting motion to the shaft to move the cutting tip against the tissue to cut tissue fragments from the tissue, and means for removing the tissue fragments along the shaft by suction to a location outside the tissue mass while cutting. The apparatus may include means for collecting one or more selected components of the harvested tissue fragments for implantation of the fragments preferably into the body of the patient from whom they were removed. Where the tissue to be cut is bone, a cutting tip is preferably made of a polymeric material which is softer than the cortical portion of the bone, although the cutting tip may be made of a ceramic or a composite material. A second flexible shaft may be provided either within or about the flexible drill shaft. The harvested tissue fragments may be implanted in the donor patient's body.

Claims (52)

1. A method of using human tissue, said method comprising the steps of removing blood from a human patient, centrifuging the blood removed from the human patient to at least partially remove a component from the blood, placing tissue graft material and the component from the blood into a mold, pressing at least one of the tissue graft material and the component from the blood in the mold to form an implant, removing the implant from the mold, and implanting the implant in the patient from which the blood was removed.

2. A method as set forth in claim 1 wherein the implant includes collagen.

3. A method as set forth in claim 1 wherein tho implant includes antibiotics.

4. A method as set forth in claim 1 wherein, the implant includes hydroxyapatite.

5. A method as set forth in claim 1 wherein said step of implanting the implant in the patient includes implanting the implant in a bone in the patient's body.

6. A method as set forth in claim 1 wherein said step of implanting the implant in the patient includes positioning the implant in a biodegradable retainer and positioning the biodegradable retainer in the patient's body.

7. A method as set forth in claim 1 wherein said step of implanting the implant in the patient includes moving the implant through a cannula to a desired location in the human patient.

8. A method as set forth in claim 1 wherein said step of removing blood from a human patient includes conducting the blood from the patient under the influence of suction.

9. A method of using human tissue, said method comprising the steps of removing blood from the human patient, centrifuging blood removed from the human patient to at least partially remove one or more components from the blood, and implanting in the patient a blood component remaining after centrifliging the blood, wherein said step of implanting a blood component in the patient includes moving a biodegradable bag into the patient.

10. A method of using human tissue, said method comprising the steps of removing tissue from a first location in a human patient, and implanting at least a portion of the tissue at a second location in the human patient, said step of implanting at least a portion of the tissue at a second location in the human patient includes moving a biodegradable bag to the second location in the human patient.

11. A method as set forth in claim 10 wherein said step of implanting the tissue at the second location in the human patient includes moving at least a portion of the tissue removed from the first location in the human patient to the second location in the human patient.

12. A method as set forth in claim 10 wherein said step of removing tissue from a first location in a human patient includes removing blood from the human patient, said method further includes centrifuging blood removal from the human patient to at least partially remove one or more components from the blood, said step of implanting the tissue at the second location in the human patient includes moving at least a portion of the blood to the second location in the human patient after centrifuging the blood.

13. A method as set forth in claim 10 wherein said step of moving the biodegradable bag to the second location in the human patient includes moving the biodegradable bag through a cannula.

14. A method as set forth in claim 10 wherein said step of implanting at least a portion of the tissue at the second location in the human patient includes moving the human tissue through a cannula with the human tissue in the biodegradable bag.

15. A method of utilizing human tissue, said method comprising the steps of:

percutaneously harvesting tissue from bone of a human donor;

conveying the harvested tissue to a location outside the body of the donor through a sterile passage;

collecting the harvested tissue in a container operatively associated with the sterile passage;

placing tissue graft material and the harvested tissue in a form;

pressing at least one of the tissue graft material and harvested tissue in the font to create a tissue graft plug;

removing the tissue graft plug from the form; and

implanting the tissue graft plug into a human recipient.

16. A method as set forth in claim 15 wherein the tissue graft plug is implanted into a bone of the recipient.

17. A method as set forth in claim 16 wherein the donor and recipient are the same individual.

18. A method as set forth in claim 17 further comprising the step of separating out at least one component from the harvested tissue and wherein the tissue graft material and the at least one component are placed in the form and are pressed to create the tissue graft plug.

19. A method as set forth in claim 18 wherein a fitter is used for the separation step.

20. A method as set forth in claim 18 wherein centrifugation is used for the separation step.

21. A method as set forth in claim 17 wherein the tissue graft plug includes viable tissue.

22. A method as set forth in claim 17 wherein the tissue graft plug includes fibrin.

23. A method as set forth in claim 17 further comprising the step of adding a bone growth promoting substance to the tissue graft plug.

24. A method as set forth in claim 23 wherein the bone growth promoting substance is hydroxyapatite or tricalcium phosphate.

25. A method as set forth in claim 17 further comprising the step of adding collagen to the tissue graft plug.

26. A method as set forth in claim 17 further comprising the step of adding an antibiotic to the tissue graft plug.

27. A method as set forth in claim 16 further comprising the step of passing the harvested tissue through a filter.

28. A method as set forth in claim 27 wherein the tissue graft plug includes viable tissue.

29. A method as set forth in claim 28 wherein the donor and recipient are the same individual.

30. A method of utilizing human tissue, said method comprising the steps of:

harvesting tissue from a human patient;

removing blood from the harvested tissue;

separating a blood component from the removed blood;

combining the blood component with the harvested tissue to form an implant; and

implanting the implant into the human patient,

wherein prior to implantation the implant is compressed in a mold.

31. A method as set forth in claim 30 wherein the tissue is bone tissue.

32. A method as set forth in claim 31 wherein a filter is used for the separation step.

33. A method as set forth in claim 31 wherein centrifugation is used for the separation step.

34. A method as set forth in claim 33 wherein the implant includes viable tissue.

35. A method as set forth in claim 31 wherein the blood component includes fibrin.

36. A method as set forth in claim 31 further comprising the step of adding a bone growth promoting substance to the implant prior to implantation.

37. A method as set forth in claim 36 wherein the bone growth promoting substance is hydroxyapatite or tricalcium phosphate.

38. A method as set forth in claim 31 further comprising the step of adding collagen to the implant prior to implantation.

39. A method as set forth in claim 31 further comprising the step of adding an antibiotic to the implant prior to implantation.

Assignments (7)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 14, 2012
From: ADVANCED SKELETAL INNOVATIONS LLC
To: BONUTTI SKELETAL INNOVATIONS LLC
Reel/Frame 028959/0109 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 12, 2012
From: ACACIA RESEARCH GROUP LLC
To: ADVANCED SKELETAL INNOVATIONS LLC
Reel/Frame 028948/0803 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 10, 2012
From: P TECH LLC
To: ACACIA RESEARCH GROUP LLC
Reel/Frame 028930/0557 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 22, 2009
From: MARCTEC, LLC
To: P TECH, LLC.
Reel/Frame 022859/0060 →
CHANGE OF NAME Recorded May 11, 2006
From: BONUTTI IP, LLC
To: MARCTEC, LLC
Reel/Frame 017603/0207 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 12, 2005
From: THE BONUTTI 2003 TRUST-A AND THE BONUTTI 2003 TRUST-B
To: BONUTTI IP, LLC
Reel/Frame 015552/0342 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 8, 2003
From: BONUTTI, PETER M.
To: BONUTTI 2003 TRUST-A, THE
Reel/Frame 013903/0070 →