Amide derivative
View Patent ↗A compound of the formula: wherein Ar is optionally substituted phenyl, etc.; n is 0, 1 or 2; R 1 is hydogen atom, optionally substituted alkyl, etc.; R 2 and R 3 are independently optionally substituted alkyl, etc.; R 4 and R 5 are independently hydrogen atom or optionally substituted alkyl; R 6 is hydrogen atom, hydroxy or alkyl; or a pharmaceutically acceptable salt thereof is useful as a medicament for treating retinal degenerative disorders and the like.
1. N-t-Butyl-2,4-difluorobenzamide, N-(2-hydroxy-1,1-dimethylethyl)-2,4-difluorobenzamide, or a pharmaceutically acceptable salt thereof.
2. A compound of the formula:
R 1 is methyl, ethyl, hydroxymethyl or hydroxyethyl and both of R 2 and R 3 are methyl,
R 6 is hydrogen atom, hydroxy or alkyl;
or a pharmaceutically acceptable salt thereof.
3. A compound or a pharmaceutically acceptable salt thereof according to claim 2 , wherein R 6 is a hydrogen.