IP Library Granted Patent US 7,056,318
Granted Patent B2
US 7,056,318 · App. 10/121,236 · Granted Jun 6, 2006

Temperature controlled heating device and method to heat a selected area of a biological body

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Quick Facts
Patent No.
US 7,056,318
App. No.
10/121,236
Granted
Jun 6, 2006
Kind
B2
Abstract

A heating device and method are provided that control a temperature in a selected area of a body part to obtain a temperature effect within the selected area for therapeutic or medical purposes. It includes temperature generating means to generate a temperature in the selected area. It also includes temperature detecting means to detect the generated temperature from the selected area. It further includes temperature controlling means to control the temperature generating means to maintain the generated temperature within a range of a desired temperature. The device and method prevent irreversibly damaging or overheating the selected area or the tissue surrounding the selected area. It is advantageous to applications where there is a need to accurately control the temperature in a selected area in a biological body, for instance, to activate or evaporate a temperature sensitive agent in the selected area.

Claims (65)

1. A device for noninvasively controlling a temperature in a selected area of a biological body, comprising:

(a) at least one temperature generating means to generate a temperature in said selected area of said biological body, wherein said at least one temperature generating means comprises a scanning means to scan a radiation generated by said at least one temperature generating means over said selected area of said biological body, wherein said at least one temperature generating means further comprises a light source, wherein said light source is one of a halogen lamp, a laser, and an arc lamp;

(b) at least one temperature detecting means to detect said generated temperature from said selected area of said biological body; and

(c) at least one temperature controlling means to control said at least one temperature generating means to maintain said generated temperature within a range of a desired temperature, wherein said at least one temperature controlling means comprises a calculating means to compensate for temperature tissue effects.

2. A device for noninvasively controlling a temperature in a selected area of a biological body, comprising:

(a) at least one temperature generating means to generate a temperature in said selected area of said biological body, wherein said at least one temperature generating means comprises a scanning means to scan a radiation generated by said at least one temperature generating means over said selected area of said biological body;

(b) at least one temperature detecting means to detect said generated temperature from said selected area of said biological body;

(c) at least one temperature controlling means to control said at least one temperature generating means to maintain said generated temperature within a range of a desired temperature, wherein said at least one temperature controlling means comprises a calculating means to compensate for temperature tissue effects; and

(d) at least one focusing means to focus said radiation generated by said at least one temperature generating means to said selected area of said biological body.

3. The device as set forth in claim 2 wherein said desired temperature is above a normal body temperature.

4. The device as set forth in claim 2 wherein said generated temperature is maintained within less than 1° C. of said desired temperature.

5. The device as set forth in claim 2 , wherein said desired temperature activates a temperature sensitive agent in said selected area, wherein said desired temperature is above a normal body temperature.

6. The device as set forth in claim 2 , wherein said desired temperature evaporates a temperature sensitive agent in said selected area, wherein said desired temperature is above a normal body temperature.

7. The device as set forth in claim 2 , wherein said at least one temperature detecting means comprises at least one infrared measuring device.

8. The device as set forth in claim 2 , further comprising at least one displaying means to display said generated temperature.

9. The device as set forth in claim 2 , wherein said device is a flexible device that comfortably fits to a body part.

10. A method for noninvasively controlling a temperature in a selected area of a biological body, comprising:

(a) generating a temperature in said selected area of said biological body with at least one temperature generating means;

(b) providing a scanning means to scan a radiation generated by said at least one temperature generating means over said selected area of said biological body;

(c) detecting said generated temperature from said selected area of said biological body with at least one temperature detecting means; and

(d) controlling said at least one temperature generating means to maintain said generated temperature within a range of a desired temperature with at least one temperature controlling means, wherein controlling said at least one temperature generating means comprises compensating for temperature tissue effects.

11. The method as set forth in claim 10 , further comprising displaying said generated temperature.

12. The method as set forth in claim 10 , wherein detecting said generated temperature comprises scanning over said selected area of said biological body to detect said generated temperature from said selected area of said biological body.

13. An endoscopic device for controlling a temperature in a selected area of a biological body, comprising:

(a) at least one temperature generating means to generate a temperature in said selected area of said biological body, wherein said at least one temperature generating means comprises a scanning means to scan a radiation generated by said at least one temperature generating means over said selected area of said biological body, wherein said at least one temperature generating means further comprises a light source;

(b) at least one temperature detecting means to detect said generated temperature from said selected area of said biological body, wherein said at least one temperature detecting means comprises at least one infrared measuring device; and

(c) at least one temperature controlling means to facilitate selection of a desired temperature and to control said at least one temperature generating means to maintain said generated temperature within less than 1° C. of said desired temperature.

14. The endoscopic device as set forth in claim 13 , wherein said light source is one of a halogen lamp, a laser, and an arc lamp.

15. The endoscopic device as set forth in claim 13 , wherein said at least one temperature generating means further comprises a RE generator.

16. The endoscopic device as set forth in claim 13 , wherein said desired temperature is above a normal body temperature.

17. The endoscopic device as set forth in claim 13 , wherein said desired temperature activates a temperature sensitive agent in said selected area, wherein said desired temperature is above a normal body temperature.

18. The endoscopic device as set forth in claim 13 , wherein said desired temperature evaporates a temperature sensitive agent in said selected area, wherein said desired temperature is above a normal body temperature.

19. The endoscopic device as set forth in claim 13 , further comprising at least one displaying means to display said generated temperature.

20. The endoscopic device as set forth in claim 13 , wherein said at least one temperature detecting means further comprises a scanning means to scan over said selected area of said biological body to detect said generated temperature from said selected area of said biological body.

21. An endoscopic device for controlling a temperature in a selected area of a biological body, comprising:

(a) at least one temperature generating means to generate a temperature in said selected area of said biological body, wherein said at least one temperature generating means comprises a scanning means to scan a radiation generated by said at least one temperature generating means over said selected area of said biological body;

(b) at least one temperature detecting means to detect said generated temperature from said selected area of said biological body, wherein said at least one temperature detecting means comprises at least one infrared measuring device;

(c) at least one temperature controlling means to facilitate selection of a desired temperature and to control said at least one temperature generating means to maintain said generated temperature within less than 1° C. of said desired temperature; and

(d) at least one focusing means to focus a radiation generated by said at least one temperature generating means to said selected area of said biological body.

22. A method for endoscopically controlling a temperature in a selected area of a biological body, comprising:

(a) facilitating selection of a desired temperature range with at least one temperature controlling means;

(b) generating a temperature in said selected area of said biological body with at least one temperature generating means, wherein said at least one temperature generating means comprises a light source;

(c) providing a scanning means to scan a radiation generated by said at least one temperature generating means over said selected area of said biological body;

(d) detecting said generated temperature from said selected area of said biological body with at least one temperature detecting means; and

(e) controlling said at least one temperature generating means to maintain said generated temperature within said desired temperature range with said at least one temperature controlling means.

23. The method as set forth in claim 22 , further comprising focusing a radiation generated by said at least one temperature generating means to said selected area of said biological body.

24. The method as set forth in claim 22 , wherein controlling said at least one temperature generating means comprises compensating for temperature tissue effects.

25. The method as set forth in claim 22 , further comprising displaying said generated temperature.

26. The method as set forth in claim 22 , wherein detecting said generated temperature comprises scanning over said selected area of said biological body to detect said generated temperature from said selected area of said biological body.

27. A device for evaporating a temperature sensitive agent in a selected area of a biological body by controlling a temperature in said selected area of said biological body, comprising:

(a) at least one temperature generating means to generate a temperature in said selected area of said biological body;

(b) at least one temperature detecting means to detect said generated temperature from said selected area of said biological body, wherein said at least one temperature detecting means comprises a scanning means to scan over said selected area of said biological body to detect said generated temperature; and

(c) at least one temperature controlling means to control said at least one temperature generating means to maintain said generated temperature within a range of a desired temperature, wherein said desired temperature evaporates said temperature sensitive agent, and wherein said at least one temperature controlling means comprises a calculating means to compensate for temperature tissue effects.

28. The device as set forth in claim 27 , wherein said device is a noninvasive device.

29. The device as set forth in claim 27 , wherein said device is configured for endoscopic use.

30. A method for evaporating a temperature sensitive agent in a selected area of a biological body by controlling a temperature in said selected area of said biological body, comprising:

(a) providing said temperature sensitive agent in said selected area of said biological body;

(b) facilitating selection of a desired temperature that evaporates said temperature sensitive agent with at least one temperature controlling means;

(c) generating a temperature in said selected area of said biological body with at least one temperature generating means;

(d) detecting said generated temperature from said selected area of said biological body with at least one temperature detecting means; and

(e) controlling said temperature generating means to obtain said generated temperature within a range of said desired temperature with said at least one temperature controlling means.

31. A device for noninvasively controlling a temperature in a selected area of a biological body, comprising:

(a) at least one temperature generating means to generate a temperature in said selected area of said biological body, wherein said at least one temperature generating means comprises a scanning means to scan a radiation generated by said at least one temperature generating means over said selected area of said biological body, wherein said at least one temperature generating means further comprises a RF generator;

(b) at least one temperature detecting means to detect said generated temperature from said selected area of said biological body; and

(c) at least one temperature controlling means to control said at least one temperature generating means to maintain said generated temperature within a range of a desired temperature, wherein said at least one temperature controlling means comprises a calculating means to compensate for temperature tissue effects.

Assignments (18)
RELEASE OF SECURITY INTEREST Recorded Nov 20, 2025
From: THE BANK OF NEW YORK MELLON, AS NOTES COLLATERAL AGENT
To: BAUSCH HEALTH COMPANIES INC.; BAUSCH HEALTH, CANADA INC.; BAUSCH HEALTH IRELAND LIMITED; SOLTA MEDICAL IRELAND LIMITED
Reel/Frame 073654/0300 →
RELEASE OF SECURITY INTEREST Recorded Nov 20, 2025
From: THE BANK OF NEW YORK MELLON, AS NOTES COLLATERAL AGENT
To: BAUSCH & LOMB INCORPORATED; BAUSCH HEALTH US, LLC; SOLTA MEDICAL, INC.; MEDICIS PHARMACEUTICAL CORPORATION; SALIX PHARMACEUTICALS, INC.; SALIX PHARMACEUTICALS, LTD.; SANTARUS, INC.; ORAPHARMA, INC.; PRECISION DERMATOLOGY, INC.; BAUSCH HEALTH AMERICAS, INC.
Reel/Frame 073654/0242 →
RELEASE OF SECURITY INTEREST Recorded Nov 20, 2025
From: THE BANK OF NEW YORK MELLON, AS NOTES COLLATERAL AGENT
To: BAUSCH HEALTH AMERICAS, INC.; BAUSCH & LOMB INCORPORATED; BAUSCH HEALTH US, LLC; SOLTA MEDICAL, INC.; MEDICIS PHARMACEUTICAL CORPORATION; SALIX PHARMACEUTICALS, INC.; SALIX PHARMACEUTICALS, LTD.; SANTARUS, INC.; ORAPHARMA, INC.; PRECISION DERMATOLOGY, INC.
Reel/Frame 073637/0126 →
RELEASE OF SECURITY INTEREST Recorded Apr 8, 2025
From: BARCLAYS BANK PLC, AS COLLATERAL AGENT
To: SOLTA MEDICAL, INC.; PRECISION DERMATOLOGY, INC.; BAUSCH HEALTH IRELAND LIMITED (F/K/A/ VALEANT PHARMACEUTICALS IRELAND LIMITED); SALIX PHARMACEUTICALS, INC.; SALIX PHARMACEUTICALS, LTD; SANTARUS, INC.; MEDICIS PHARMACEUTICAL CORPORATION; HUMAX PHARMACEUTICAL S.A.; SOLTA MEDICAL IRELAND LIMITED; BAUSCH & LOMB MEXICO, S.A. DE C.V.; BAUSCH+LOMB OPS B.V.; BAUSCH HEALTH AMERICAS, INC.; BAUSCH HEALTH COMPANIES INC.; BAUSCH HEALTH HOLDCO LIMITED; BAUSCH HEALTH MAGYARORSZAG KFT (A/K/A BAUSCH HEALTH HUNGARY LLC); BAUSCH HEALTH POLAND SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA (F/K/A VALEANT PHARMA POLAND SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA); BAUSCH HEALTH US, LLC; BAUSCH HEALTH, CANADA INC. / SANTE BAUSCH, CANADA INC.; ICN POLFA RZESZOW SPOLKA AKCYJNA (A/K/A ICN POLFA RZESZOW S.A.); ORAPHARMA, INC.; PRZEDSIEBIORSTWO FARMACEUTYCZNE JELFA SPOLKA AKCYJNA (A/K/A PRZEDSIEBIORSTWO FARMACEUTYCZNE JELFA S.A.); SOLTA MEDICAL DUTCH HOLDINGS B.V.; V-BAC HOLDING CORP.; VRX HOLDCO LLC; 1261229 B.C. LTD.; 1530065 B.C. LTD.
Reel/Frame 070778/0199 →
INTELLECTUAL PROPERTY SECURITY AGREEMENT Recorded Jun 9, 2023
From: BAUSCH HEALTH IRELAND LIMITED; SOLTA MEDICAL IRELAND LIMITED; MEDICIS PHARMACEUTICAL CORPORATION; ORAPHARMA, INC.; SALIX PHARMACEUTICALS, INC.; SOLTA MEDICAL, INC.; PRECISION DERMATOLOGY, INC.
To: BARCLAYS BANK PLC, AS COLLATERAL AGENT
Reel/Frame 063942/0001 →
SECURITY AGREEMENT (SECOND LIEN) Recorded Oct 5, 2022
From: BAUSCH HEALTH US, LLC; BAUSCH HEALTH AMERICAS, INC.; MEDICIS PHARMACEUTICAL CORPORATION; ORAPHARMA, INC.; PRECISION DERMATOLOGY, INC.; SALIX PHARMACEUTICALS, INC.; SALIX PHARMACEUTICALS, LTD.; SANTARUS, INC.; SOLTA MEDICAL, INC.
To: THE BANK OF NEW YORK MELLON, AS NOTES COLLATERAL AGENT
Reel/Frame 061606/0468 →
SECURITY AGREEMENT (FIRST LIEN) Recorded Oct 4, 2022
From: BAUSCH HEALTH US, LLC; BAUSCH HEALTH AMERICAS, INC.; MEDICIS PHARMACEUTICAL CORPORATION; ORAPHARMA, INC.; PRECISION DERMATOLOGY, INC.; SALIX PHARMACEUTICALS, INC.; SALIX PHARMACEUTICALS, LTD.; SANTARUS, INC.; SOLTA MEDICAL, INC.
To: THE BANK OF NEW YORK MELLON, AS NOTES COLLATERAL AGENT
Reel/Frame 061595/0066 →
SECURITY INTEREST Recorded Jun 13, 2022
From: BAUSCH HEALTH COMPANIES INC.; BAUSCH HEALTH, CANADA INC.; BAUSCH HEALTH IRELAND LIMITED; SOLTA MEDICAL IRELAND LIMITED
To: THE BANK OF NEW YORK MELLON
Reel/Frame 060346/0705 →
SECURITY AGREEMENT Recorded Feb 10, 2022
From: BAUSCH & LOMB INCORPORATED; BAUSCH HEALTH US, LLC; SOLTA MEDICAL, INC.; MEDICIS PHARMACEUTICAL CORPORATION; SALIX PHARMACEUTICALS, INC.; SALIX PHARMACEUTICALS, LTD.; SANTARUS, INC.; ORAPHARMA, INC.; PRECISION DERMATOLOGY, INC.; BAUSCH HEALTH AMERICAS, INC.
To: THE BANK OF NEW YORK MELLON
Reel/Frame 059121/0001 →
SECURITY INTEREST Recorded Jun 8, 2021
From: BAUSCH & LOMB INCORPORATED; BAUSCH HEALTH US, LLC; SOLTA MEDICAL, INC.; MEDICIS PHARMACEUTICAL CORPORATION; SALIX PHARMACEUTICALS, INC.; SALIX PHARMACEUTICALS, LTD.; SANTARUS, INC.; ORAPHARMA, INC.; PRECISION DERMATOLOGY, INC.; BAUSCH HEALTH AMERICAS, INC.
To: THE BANK OF NEW YORK MELLON, AS NOTES COLLATERAL AGENT
Reel/Frame 056811/0814 →
MERGER Recorded May 14, 2021
From: RELIANT TECHNOLOGIES, LLC
To: SOLTA MEDICAL, INC.
Reel/Frame 056244/0936 →
MERGER Recorded May 12, 2021
From: RELIANT TECHNOLOGIES, INC.
To: RELIANT TECHNOLOGIES, LLC
Reel/Frame 056218/0067 →
SECURITY INTEREST Recorded Mar 11, 2019
From: BAUSCH HEALTH AMERICAS, INC.; BAUSCH & LOMB INCORPORATED; BAUSCH HEALTH US, LLC; SOLTA MEDICAL, INC.; MEDICIS PHARMACEUTICAL CORPORATION; SALIX PHARMACEUTICALS, INC.; SALIX PHARMACEUTICALS, LTD.; SANTARUS, INC.; ORAPHARMA, INC.; PRECISION DERMATOLOGY, INC.
To: THE BANK OF NEW YORK MELLON, AS NOTES COLLATERAL AGENT
Reel/Frame 048556/0758 →
RELEASE OF SECURITY INTEREST IN PATENTS Recorded Jan 27, 2014
From: SILICON VALLEY BANK
To: RELIANT TECHNOLOGIES, LLC
Reel/Frame 032125/0810 →
RELEASE OF SECURITY INTEREST IN PATENTS Recorded Jan 24, 2014
From: CAPITAL ROYALTY PARTNERS II L.P.; CAPITAL ROYALTY PARTNERS II - PARALLEL FUND "A" L.P.; PARALLEL INVESTMENT OPPORTUNITIES PARTNERS II L.P.
To: RELIANT TECHNOLOGIES, LLC
Reel/Frame 032126/0708 →
SHORT-FORM PATENT SECURITY AGREEMENT Recorded Nov 19, 2013
From: RELIANT TECHNOLOGIES, LLC
To: CAPITAL ROYALTY PARTNERS II L.P.; CAPITAL ROYALTY PARTNERS II - PARALLEL FUND "A" L.P.; PARALLEL INVESTMENT OPPORTUNITIES PARTNERS II L.P.
Reel/Frame 031674/0527 →
SECURITY INTEREST - MEZZANINE LOAN Recorded Apr 18, 2013
From: RELIANT TECHNOLOGIES, LLC
To: SILICON VALLEY BANK
Reel/Frame 030248/0256 →
SECURITY AGREEMENT Recorded Jun 16, 2009
From: RELIANT TECHNOLOGIES, LLC
To: SILICON VALLEY BANK
Reel/Frame 022824/0847 →