Antigenic proteins of shrimp white spot syndrome virus and uses thereof
The present invention relates to antigenic proteins derived from White Spot Syndrome virus having an estimated size of 19 kDa (VP 19) or 13 kDA (VP13), to the use of these proteins in vaccines and to vaccines on the basis of these proteins. Furthermore, the invention relates to antibodies against these proteins and to the use of antibodies in vaccines, to nucleic acid sequences encoding these proteins and to their use in vaccines. Also, the invention relates to the use of said proteins in the manufacture of a vaccine for prophylaxis and/or treatment of White Spot Syndrome in crustaceans, to vector vaccines and to diagnostic kits comprising said nuclei acids or antibodies.
1. A composition suitable for immunizing crustaceans by injection against White Spot Syndrome Virus, WSSV, comprising:
an isolated protein consisting of an amino acid sequence represented by SEQ ID NO: 2, wherein the composition delays mortality against WSSV infectivity in crustaceans.
2. An injectable vaccine capable of delaying mortality against WSSV infectivity in crustaceans, comprising:
a composition according to claim 1 , and
a pharmaceutically acceptable carrier.
3. An isolated nucleic acid sequence encoding an isolated protein consisting of an amino acid sequence represented by SEQ ID NO: 2.
4. A diagnostic kit for detection of WSSV, comprising:
an isolated protein encoded by an isolated nucleic acid sequence represented by SEQ ID NO: 1.
5. An isolated protein consisting of an amino acid sequence represented by SEQ ID NO: 2.