IP Library › Granted Patent US 7,030,106
Granted Patent B2
US 7,030,106 · App. 10/136,968 · Granted Apr 18, 2006

Sterol absorption inhibitor compositions

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Quick Facts
Patent No.
US 7,030,106
App. No.
10/136,968
Granted
Apr 18, 2006
Kind
B2
Abstract

The present invention provides compositions, therapeutic combinations and methods including: (a) at least one peroxisome proliferator-activated receptor activator; and (b) at least one substituted azetidinone or substituted β-lactam sterol absorption inhibitor which can be useful for treating vascular conditions, diabetes, obesity and lowering plasma levels of sterols.

Claims (42)

1. A pharmaceutical composition consisting of:

Weight percent

Ingredient

of ingredient

Compound of Formula (II)

10

Lactose monohydrate

55

Microcrystalline cellulose

20

Povidone

4

Croscarmellose sodium

8

Sodium lauryl sulfate

2

Magnesium stearate

1

Total

100

wherein the compound represented by Formula (II) below is:

2. A pharmaceutical composition consisting essentially of:

milligrams of

Ingredient

ingredient

Compound of Formula (II)

10

Lactose monohydrate

55

Microcrystalline cellulose

20

Povidone

4

Croscarmellose sodium

8

Sodium lauryl sulfate

2

Magnesium stearate

1

Total

100

wherein the compound represented by Formula (II) below is:

Assignments (5)
INTELLECTUAL PROPERTY SECURITY AGREEMENT - CREDIT AGREEMENT Recorded Jun 3, 2021
From: ORGANON LLC
To: JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT
Reel/Frame 056463/0465 →
INTELLECTUAL PROPERTY SECURITY AGREEMENT - (EURO NOTES) Recorded Jun 3, 2021
From: ORGANON LLC
To: U.S. BANK, NATIONAL ASSOCIATION , AS COLLATERAL AGENT
Reel/Frame 056464/0421 →
INTELLECTUAL PROPERTY SECURITY AGREEMENT - (DOLLAR NOTES) Recorded Jun 3, 2021
From: ORGANON LLC
To: U.S. BANK, NATIONAL ASSOCIATION , AS COLLATERAL AGENT
Reel/Frame 056467/0001 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 19, 2021
From: MERCK SHARP & DOHME CORP.
To: ORGANON LLC
Reel/Frame 056285/0013 →
CHANGE OF NAME Recorded Aug 30, 2012
From: SCHERING CORPORATION
To: MERCK SHARP & DOHME CORP.
Reel/Frame 028884/0151 →