IP Library › Granted Patent US 7,101,987
Granted Patent B2
US 7,101,987 · App. 10/146,496 · Granted Sep 5, 2006

CCL27 polypeptides

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Quick Facts
Patent No.
US 7,101,987
App. No.
10/146,496
Granted
Sep 5, 2006
Kind
B2
Abstract

Novel CC chemokines from human, reagents related thereto including purified proteins, specific antibodies and nucleic acids encoding these chemokines are provided. Also provided are methods of making and using said reagents and diagnostic kits.

Claims (9)

1. An isolated polypeptide comprising the amino acid sequence of SEQ ID NO: 6 or an antigenic fragment comprising 10 or more contiguous amino acids thereof.

2. The polypeptide of claim 1 comprising 20 contiguous amino acids of SEQ ID NO: 6.

3. The polypeptide of claim 2 comprising 30 contiguous amino acids of SEQ ID NO: 6.

4. A pharmaceutical composition comprising the polypeptide of claim 1 in conjunction with a suitable carrier.

5. A method of producing a polypeptide of claim 1 comprising culturing a host cell comprising a polynucleotide encoding said polypeptide under conditions suitable for the expression of said polypeptide and recovering the polypeptide from the culture.

6. The polypeptide of claim 1 bound to human CCR10.

7. The polypeptide of claim 3 comprising 50 contiguous amino acids of SEQ ID NO: 6.

8. The polypeptide of claim 7 comprising 70 contiguous amino acids of SEQ ID NO: 6.

9. An isolated polypeptide comprising the amino acid sequence of SEQ ID NO: 6.

Assignments (1)
CHANGE OF NAME Recorded Aug 30, 2012
From: SCHERING CORPORATION
To: MERCK SHARP & DOHME CORP.
Reel/Frame 028884/0151 →