Compositions and methods for the induction of retinal detachments

1. A method comprising the steps of:

administering by ocular route a dose of a glycol ether effective to induce retinal detachment;

translocating a portion of retinal tissue from a first position to a second position; and reattaching said portion of retinal tissue.

2. The method of claim 1 , further comprising the administration of an effective dose of a vitreal humor liquefying agent.

3. A method comprising:

(a) identifying a patient in need of retinal detachment; and

(b) administering by ocular route a dose of a glycol ether effective to induce retinal detachment.

4. A method comprising:

(a) administering by ocular route a dose of glycol ether effective to induce retinal detachment; and

(b) measuring retinal detachment.

5. The method of claim 3 or 4 , further comprising the administration of an effective dose of a vitreal humor liquefying agent.

6. The method of claim 5 , wherein said vitreal humor liquefying agent is selected from the group consisting of glycosaminoglycanases; chondroitin sulfatases; matrix metalloproteinases; and protein-kinases.

7. The method of claim 6 , wherein said glycosaminoglycanases are selected from the group consisting of hyaluronidase, hexosaminidase, endo-β-glucuronidase, keratinase, chondroitinase AC, chondroitinase B and chondroitinase ABC.

8. The method of claim 6 , wherein said chondroitin sulfatases are selected from the group consisting of chondroitin 4 sulfatase and chondroitin 6 sulfatase.

9. The method of claim 6 , wherein said matrix metalloproteinases are selected from the group consisting of matrix metalloproteinase 1, matrix metalloproteinase 2, matrix metalloproteinase 3 and matrix metalloproteinase 9.

10. The method of claim 6 , wherein said protein-kinases are selected from the group consisting of streptokinase and urokinase.