IP Library Granted Patent US 6,991,645
Granted Patent B2
US 6,991,645 · App. 10/160,611 · Granted Jan 31, 2006

Patient temperature regulation method and apparatus

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Quick Facts
Patent No.
US 6,991,645
App. No.
10/160,611
Granted
Jan 31, 2006
Kind
B2
Abstract

A device and method for providing body cooling. The cooling device applies cooling to blood flowing in a vena cavae that is then distributed throughout the body. The cooling can be assisted by use of thermoregulatory drugs or warming devices to prevent shivering and vasoconstriction.

Claims (17)

1. A method for cooling a patient's body intravascularly, comprising:

providing a catheter having a cooling element attached to a distal end thereof, the cooling element having mixing-inducing surface features thereon;

inserting the catheter through the vascular system of the patient to place the cooling element in a vein that drains into the heart of a patient;

circulating fluid through the cooling element; and

transferring heat from the blood in the vein to the cooling element, further comprising applying cooling via a cooling device to a substantial portion of the surface area of the patient.

2. The method of claim 1 , wherein the cooling device is a cooling blanket.

3. The method of claim 1 , further comprising administering a thermoregulatory drug to the patient.

4. A method of treating a human body, comprising:

inserting a flexible conductive heat transfer element into a vein from a distal location, the flexible heat transfer element having mixing-inducing surface features on the surface thereof;

circulating a working fluid through the flexible conductive heat transfer element to modify the temperature of the blood in the vein, thereby modifying the temperature of the body; and

modifying the temperature of at least a portion of the surface of the human body by a surface cooler.

5. The method of claim 4 , wherein said mixing-inducing features create a turbulence intensity of at least about 0.05.

6. The method of claim 5 , wherein said mixing-inducing features include at least one helical invagination.

7. The method of claim 5 , wherein said mixing-inducing features include at least one protrusion.

8. The method of claim 5 , wherein said mixing-inducing features create a mixing characterized by a Nusselt number of at least about 5.

9. The method of claim 8 , wherein said mixing-inducing features include at least one helical invagination.

10. The method of claim 8 , wherein said mixing-inducing features include at least one protrusion.

Assignments (6)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 13, 2014
From: INNERCOOL THERAPIES, INC.
To: PHILIPS ELECTRONICS NORTH AMERICA CORPORATION
Reel/Frame 033975/0849 →
SECURITY AGREEMENT Recorded Mar 9, 2009
From: INNERCOOL THERAPIES, INC.
To: MARSHALL, ROBERT
Reel/Frame 022380/0013 →
SECURITY AGREEMENT Recorded Nov 5, 2008
From: INNERCOOL THERAPIES, INC.
To: MARVIN, ROBERT
Reel/Frame 021794/0394 →
RELEASE OF SECURITY INTEREST Recorded Jul 15, 2008
From: LIFE SCIENCES CAPITAL, LLC
To: INNERCOOL THERAPIES, INC.
Reel/Frame 021230/0753 →
SECURITY AGREEMENT Recorded Nov 16, 2007
From: INNERCOOL THERAPIES, INC.
To: LIFE SCIENCES CAPITAL, LLC
Reel/Frame 020125/0289 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 31, 2007
From: INNERCOOL THERAPIES, INC., A CALIFORNIA CORPORATION
To: INNERCOOL THERAPIES, INC., A DELAWARE CORPORATION
Reel/Frame 019781/0492 →