PRO1083 polypeptides
View Patent ↗The present invention is directed to novel seven transmembrane polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
1. An isolated polypeptide comprising the amino acid sequence shown as SEQ ID NO:483.
2. An isolated polypeptide comprising the amino acid sequence shown as SEQ ID NO:483, lacking its associated signal peptide.
3. An isolated polypeptide comprising the amino acid sequence of the polypeptide encoded by the full-length coding sequence of the cDNA deposited under ATCC accession number 209859.
4. A chimeric polypeptide comprising a polypeptide according to claim 1 fused to a heterologous polypeptide.
5. The chimeric polypeptide of claim 4 , wherein said heterologous polypeptide is an epitope tag or an Fc region of an immunoglobulin.
6. A chimeric polypeptide comprising a polypeptide according to claim 2 fused to a heterologous polypeptide.
7. The chimeric polypeptide of claim 6 , wherein said heterologous polypeptide is an epitope tag or an Fc region of an immunoglobulin.
8. A chimeric polypeptide comprising a polypeptide according to claim 3 fused to a heterologous polypeptide.
9. The chimeric polypeptide of claim 8 , wherein said heterologous polypeptide is an epitope tag or an Fc region of an immunoglobulin.