Ion exchange porous resins for solid phase extraction and chromatography
View Patent ↗Embodiments of the present invention are directed to porous resins for solid phase extractions. The resins feature at least one hydrophobic component, at least one hydrophilic component and at least one ion exchange functional group. The resins exhibit superior wetting and ion exchange performance.
1. A compound of the formula:
and salts thereof,
wherein the order of A, B and C may be random, block, or a combination of random and block;
wherein
1
100
<
(
p
+
n
)
m
<
100
1
and
1
500
<
p
n
<
100
1
wherein A is selected from the group consisting of
wherein B is selected from the group consisting of
wherein C is A or modified A, wherein modified A is selected from the group consisting of
wherein X is selected from the group consisting of SO 3 H, CH 2 CO 2 H, CH 2 CH(CO 2 H) 2 , CO 2 H, PO 3 H 2 , PO 2 H 2 , CH 2 PO 3 H 2 , CH 2 Cl, CH 2 NH 2 , CH 2 N [(CH 2 ) y CH 3 ] 2 wherein y is any integer from 0 to 18, CH 2 N + [(CH 2 ) y= CH 3 ] 3 D − wherein y= is any integer from 0 to 18 and D − is an anion, SO 2 NHR wherein R is polyethylenimine, and CH 2 NHR wherein R is polyethylenimine.
2. The compound according to claim 1 wherein X is present at a concentration of about 0.1 to about 5.0 milliequivalents per gram of compound.
3. The compound according to claim 1 wherein X is present at a concentration of about 0.6 to about 3.2 milliequivalents per gram of compound.
4. The compound according to claim 1 wherein X is present at a concentration of about 0.8 to about 2.1 milliequivalents per gram of compound.
5. The compound according to claim 1 wherein X is present at a concentration of about 1.0 milliequivalents per gram of compound.
6. The compound according to claim 1 wherein X is selected from the group consisting of SO 3 H, CH 2 PO 3 H 2 , and CH 2 CO 2 H.
7. The compound according to claim 6 wherein X is SO 3 H.