IP Library › Granted Patent US 8,653,248
Granted Patent B2
US 8,653,248 · App. 10/171,270 · Granted Feb 18, 2014

2-aminopyridine and 2-pyridone C-nucleosides

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Quick Facts
Patent No.
US 8,653,248
App. No.
10/171,270
Granted
Feb 18, 2014
Kind
B2
Abstract

The present invention provides 2-aminopyridine and 2-pyridone C-nucleosides and oligonucleotides containing the subject nucleosides. The nucleosides are useful in the preparation of the subject oligonucleotides. The oligonucleotides are useful in oligonucleotide-based diagnosis and separation through triplex binding.

Claims (4)

1. An oligomer compound comprising a multiplicity of nucleosides linked by internucleoside linkages wherein at least one nucleoside is a 2-aminopyridine or 2-pyridone C-nucleoside.

2. The compound of claim 1 that is an oligonucleotide.

3. The compound of claim 1 wherein at least one nucleoside is 2-aminopyridine.

4. The compound of claim 1 wherein at least one nucleoside is a 2-pyridone C-nucleoside.

Assignments (1)
CHANGE OF NAME Recorded Jun 28, 2017
From: ISIS PHARMACEUTICALS, INC.
To: IONIS PHARMACEUTICALS, INC.
Reel/Frame 043029/0264 →