Composition for the prevention and/or treatment of lipid metabolism disorders and allergic forms
View Patent ↗A composition is disclosed which can be used as a health food/dietary supplement or as a drug for the prevention and/or treatment of lipid metabolism disorders and allergic forms and for activating organic defences against infections and tumor processes, containing as its characterizing components isovaleryl L-carnitine and a polysaccharide selected from glucans and galactans.
1. A combination composition consisting of as active ingredients:
(a) isovaleryl L-carnitine or a pharmacologically acceptable salt thereof; and
(b) a polysaccharide selected from the group consisting of beta-glucan, beta-1,3 D-glucan, beta-1,6-D-glucan, and mixtures thereof.
2. The composition of claim 1 wherein the weight ratio of (a):(b) is from 1:0.1 to 1:10.
3. The composition of claim 2 wherein the weight ratio of (a):(b) is from 1:0.5 to 1:5.
4. The composition of claim 1 wherein the pharmacologically acceptable salt is selected from the group consisting of chloride; bromide; iodide; aspartate, acid aspartate; citrate, acid citrate; tartrate; phosphate; acid phosphate; fumarate; acid fumarate; glycerophosphate; glucose phosphate; lactate; maleate; acid maleate; mucate; orotate; oxalate; acid oxalate; sulphate; acid sulphate; trichioroacetate; trifluoroacetate and methane sulphonate.
5. The composition of claim 1 which is orally administrable, in the form of a health food or dietary supplement.
6. The composition of claim 5 in the form of a solid, semisolid or liquid preparation.
7. The composition of claim 6 in the dosage form of a tablet, capsule, lozenge, pill, granulate, syrup or drop.
8. The composition of claim 7 in unit dosage form, which consists of:
Isovaleryl L-carnitine fumarate
200
mg
β-glucan
300
mg.
9. The composition of claim 1 which is orally, parenterally, rectally, sublingually or transdermally administrable, in the form of a medicament.
10. A combination composition consisting of as active ingredients:
(a) isovaleryl L-carnitine or a pharmacologically acceptable salt thereof;
(b) a polysaccharide selected from the group consisting of beta-glucan, beta-1,3 D-glucan, beta-1,6-D-glucan, and mixtures thereof; and
(c) beta-3,6-D-galactan.
11. A combination composition consisting of as the active ingredients:
(a) isovaleryl L-carnitine or a pharmacologically acceptable salt thereof;
(b) a polysaccharide selected from the group consisting of beta-glucan, beta-1,3 D-glucan, beta-1,6-D-glucan, and mixtures thereof; and
(c) a carnitine selected from the group consisting of L-carnitine, acetyl L-carnitine, propionyl L-carnitine, butyryl L-carnitine and valery L-carnitine or the pharmacologically acceptable salts or mixtures thereof.
12. The composition of claim 11 in unit dosage form, wherein (a) is 300 mg Isovaleryl L-carnitine fumarate, and (b) is 200 mg beta-1,3-D-glucan.
13. The composition of claim 11 in unit dosage form, which consists of:
Isovaleryl L-carnitine fumarate
100
mg
Propionyl L-carnitine
100
mg
Acetyl L-carnitine
100
mg
Butyryl L-carnitine
100
mg
β-1,3-D-glucan
200
mg.
14. A composition in unit dosage form, which consists of
Isovaleryl L-carnitine fumarate
200
mg
Beta-1,3-D-glucan
300
mg
Beta-3,6-D-galactan
200
mg
Beta-glucan
300
mg.
15. A combination composition in unit dosage form, which consists of as the active ingredients:
Isovaleryl L-carnitine fumarate
200
mg
L-carnitine fumarate
100
mg
β-glucan
300
mg
β-carotene
2
mg
Pyridoxine
5
mg
Folic acid
100
μg
Vit. B 12
100
μg
Vit. E
5
mg
Vit. C
50
mg
Coenzyme Q 10
50
mg.
16. A method of activating the immune system against bacterial or viral infections which comprises administering to an individual in need thereof a combination composition consisting of the following ingredients:
(a) isovaleryl L-carnitine or a pharmacologically acceptable salt thereof; and
(b) a polysaccharide selected from the group consisting of beta-glucan, beta-1,3 D-glucan, beta-1,6-D-glucan, and mixtures thereof.
17. The method of claim 16 wherein the weight ratio of (a):(b) is from 1:0.1 to 1:10.
18. The method of claim 16 wherein the weight ratio of (a):(b) is from 1:0.5 to 1:5.
19. A method of activating the immune system against bacterial or viral infections which comprises administering to an individual in need thereof a combination composition consisting of the following ingredients:
(a) isovaleryl L-carnitine or a pharmacologically acceptable salt thereof;
(b) a polysaccharide selected from the group consisting of beta-glucan, beta-1,3 D-glucan, beta-1,6-D-glucan, and mixtures thereof; and
(c) a carnitine selected from the group consisting of L-carnitine, acetyl L-carnitine, propionyl L-carnitine, butyryl L-carnitine and valery L-carnitine or the pharmacologically acceptable salts or mixtures thereof.
20. The method of claim 19 wherein the weight ratio of (a):(b) is from 1:0.1 to 1:10.
21. The method of claim 20 wherein the weight ratio of (a):(b) is from 1:0.5 to 1:5.