IP Library › Granted Patent US 8,246,969
Granted Patent B2
US 8,246,969 · App. 10/223,073 · Granted Aug 21, 2012

Compositions containing aromatic aldehydes and their use in treatments

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Quick Facts
Patent No.
US 8,246,969
App. No.
10/223,073
Granted
Aug 21, 2012
Kind
B2
Abstract

Disclosed are pharmaceutical and cosmetic compositions containing aromatic aldehyde compounds. Some of the disclosed compositions are useful as topical therapeutics for treating inflammatory dermatologic conditions. Some of the compositions are useful in transdermal and other systemic dose forms for treating other inflammatory conditions in mammals.

Claims (10)

1. A topical pharmaceutical or cosmetic composition comprising (1) a pharmaceutically or cosmetically acceptable topical carrier selected from the group consisting of a lotion, a gel, an ointment, a paste, a suspension and a cream and (2) an effective skin inflammation-alleviating amount of a benzaldehyde selected from the group consisting of 2-ethoxybenzaldehyde, 4-ethoxybenzaldehyde, 4-propoxybenzaldehyde, 4-butoxybenzaldehyde, 4-pentyloxybenzaldehyde, 4-hexyloxybenzaldehyde, and 4-allyloxybenzaldehyde, wherein the pharmaceutical composition or cosmetic composition alleviates inflammation when applied to inflamed skin, and wherein the pharmaceutical or cosmetic composition is contained in a container.

2. The topical pharmaceutical or cosmetic composition of claim 1 , wherein the benzaldehyde is 2-ethoxybenzaldehyde.

3. The topical pharmaceutical or cosmetic composition of claim 1 , wherein the benzaldehyde is 4-ethoxybenzaldehyde.

4. The topical pharmaceutical or cosmetic composition of claim 1 , wherein the benzaldehyde is 4-propoxybenzaldehyde.

5. The topical pharmaceutical or cosmetic composition of claim 1 , wherein the benzaldehyde is 4-butoxybenzaldehyde.

6. The topical pharmaceutical or cosmetic composition of claim 1 , wherein the benzaldehyde is 4-pentyloxybenzaldehyde.

7. The topical pharmaceutical or cosmetic composition of claim 1 , wherein the benzaldehyde is 4-hexyloxybenzaldehyde.

8. The composition of claim 1 wherein the carrier is a lotion carrier.

9. The composition of claim 1 wherein the carrier is a cream carrier.

10. The topical pharmaceutical or cosmetic composition of claim 1 , wherein the benzaldehyde is 4-allyloxybenzaldehyde.

Assignments (6)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 5, 2013
From: SKINMEDICA, INC.
To: ALLERGAN, INC.
Reel/Frame 029752/0926 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 23, 2012
From: MERZ AESTHETICS, INC.
To: SKINMEDICA, INC.
Reel/Frame 028255/0472 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 21, 2012
From: MERZ AESTHETICS, INC.
To: SKINMEDICA, INC.
Reel/Frame 028243/0955 →
CHANGE OF NAME Recorded Sep 1, 2010
From: BIOFORM MEDICAL, INC.
To: MERZ AESTHETICS, INC.
Reel/Frame 024925/0633 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 9, 2007
From: CUTANIX CORPORATION
To: BIOFORM MEDICAL, INC.
Reel/Frame 019936/0305 →
CORRECTIVE ASSIGNMENT TO REMOVE AN ERRONEOUS RECORDED SERIAL NUMBER 60/332,277. PREVIOUSLY RECORDED AT REEL 013622 FRAME 0290. Recorded Mar 27, 2007
From: ENGLES, CHARLES R.; FULLER, BRYAN; PILCHER, BRIAN KEITH
To: CUTANIX CORPORATION
Reel/Frame 019121/0568 →