IP Library Granted Patent US 7,029,699
Granted Patent B2
US 7,029,699 · App. 10/226,540 · Granted Apr 18, 2006

Soft chewable tablets

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Quick Facts
Patent No.
US 7,029,699
App. No.
10/226,540
Granted
Apr 18, 2006
Kind
B2
Abstract

The present invention relates to a compressed, chewable tablet containing at least one active ingredient, a water-disintegratable, compressible carbohydrate and a binder. These components are dry blended and compressed into convex-shaped tablet having a hardness of about 2 to about 11 kp/cm 2 and friability less than 1%.

Claims (12)

1. A product produced by the process, comprising the steps of:

dry mixing at least one taste-masked coated active ingredient selected from acetaminophen, a water-disintegratable, compressible carbohydrate and a binder; and

compressing the mixture into a tablet having convex shaped opposed face surfaces and a hardness of about 2 to about 11 kp/cm 2 .

2. The product of claim 1 wherein said mixture is compressed to a tablet hardness of about 5 to about 8.5 kp/cm 2 .

3. The product of claim 1 wherein said taste masking coating comprises a blend of a first polymer selected from the group consisting of a cellulose acetate and cellulose acetate butyrate and a second polymer selected from the group consisting of polyvinyl pyrrolidone and hydroxypropyl cellulose, wherein the weight ratio of the first polymer to the second polymer is within the range of about 90:10 to about 50:50.

4. The product of claim 1 wherein the compressible carbohydrate is selected form the group consisting of mannitol, sorbitol, maltitol, dextrose, sucrose, xylitol, lactose, and mixtures thereof.

5. The product of claim 1 wherein the binder is selected form the group consisting of cellulose, cellulosic derivatives, polyvinyl pyrrolidone, starch, modified starch and mixtures thereof.

6. The product of claim 1 wherein said face surfaces have a bi-convex or tri-convex shape.

7. The product of claim 6 wherein said tablet has bi-convex shaped face surfaces and a minor axis cup radius of about 10 to about 40 percent of the tablet diameter and major axis cup radius of about 100 to about 400 percent of the tablet diameter.

8. The product of claim 1 wherein said tablet has a friability of less than about 1%.

9. The process of claim 8 wherein said friability is less than about 0.5%.

10. The process of claim 1 wherein a pre-compression force is applied to said mixture before the application of a main compression force.

Assignments (1)
MERGER AND CHANGE OF NAME Recorded Jul 2, 2015
From: MCNEIL-PPC, INC.; JOHNSON & JOHNSON CONSUMER INC.
To: JOHNSON & JOHNSON CONSUMER INC.
Reel/Frame 036049/0254 →