IP Library Granted Patent US 7,044,008
Granted Patent B1
US 7,044,008 · App. 10/240,127 · Granted May 16, 2006

Collecting device for collecting objects that are dissolved out of a mass, especially by means of laser radiation

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Quick Facts
Patent No.
US 7,044,008
App. No.
10/240,127
Granted
May 16, 2006
Kind
B1
Abstract

In order to allow automatic separation and recovery of biological or non-biological objects from a mass, which is located on a mount ( 3 ), by means of laser irradiation, a collecting apparatus ( 2 ) is proposed which has control means ( 7, 50 ) for automatic production of adjustment signals for the adjustment means ( 13 ), wherein the adjustment means adjust and hence position, as a function of these adjustment signals, a holding unit ( 19 ) having at least one collecting means ( 21 ) which is or are used for collecting an object which is released from the mass.

Claims (131)

1. Collecting apparatus for collecting objects which are released, in particular by means of laser irradiation, from a mass which is located on a mount ( 3 ), having a holding unit ( 19 ) for holding at least one collecting means ( 21 ) for collecting an object which is released from the mass, and

having adjustment means ( 13 ) for adjusting the holding unit ( 19 ) in order in this way to position the holding unit ( 19 ),

characterized

in that control means ( 7 , 50 ) are provided for automatic production of adjustment signals for the adjustment means ( 13 ),

in that the adjustment means ( 13 ) are designed such that they automatically adjust the holding unit ( 19 ) in accordance with the adjustment signals from the control means ( 7 , 50 ),

in that the adjustment means ( 13 ) are designed such that when appropriate adjustment signals from the control means ( 7 ) are present they move, in particular pivot, the holding unit ( 19 ) from a placement position which is intended for fitting the holding unit ( 19 ) to the collecting apparatus ( 2 ) or for fitting the collecting means ( 21 ) to the holding unit ( 19 ), to a working position which is used for collecting an object which is released from the mass, or vice versa, and

in that the adjustment means have a first adjustment device ( 14 ) for pivoting the holding unit ( 19 ) from the placement position to the working position, or vice versa, and in that the adjustment means ( 13 ) have a second adjustment device ( 15 , 17 , 25 , 26 ), in order to adjust the holding unit ( 19 ) in the working position essentially parallel to the plane of the mount ( 3 ).

2. The collecting apparatus as claimed in claim 1 , characterized

in that the collecting apparatus ( 2 ) is designed such that, in the placement position, the holding unit ( 19 ) together with the collecting means ( 21 ) is further away, in particular raised, from the mount ( 3 ) having the mass, than in the working position.

3. The collecting apparatus as claimed in claim 2 ,

characterized

in that retention means ( 24 ) are provided for holding the holding unit ( 19 ),

in that the retention means ( 24 ) are mounted on an obliquely running contact surface ( 46 ) such that the retention means ( 24 ) are moved along the obliquely running contact surface ( 46 ) while the retention means ( 24 ) are being pivoted from the working position to the placement position and, in the process, the retention means ( 24 ) are moved away from the mount ( 3 ) in the vertical direction.

4. The collecting apparatus as claimed in claim 1 ,

characterized

in that the adjustment means ( 13 , 17 ) are designed such that, in the working position, they allow automatic adjustment of the holding unit ( 19 ) essentially parallel to the plane of the mount ( 3 ) in order to view, using a microscope, the object collected by the collecting means ( 21 ).

5. The collecting apparatus as claimed in claim 4 ,

characterized

in that a null position is defined for the collecting means ( 21 ) in the working position, and in that the control means ( 7 , 50 ) are designed such that, after adjustment of the holding unit ( 19 ) together with the collecting means ( 21 ) held by it, from the null position, by means of appropriate actuation of the adjustment means ( 13 , 17 ), said control means ( 7 , 50 ) automatically reset to the null position the holding unit ( 19 ) together with the collecting means ( 21 ) held by it.

6. The collecting apparatus as claimed in claim 4 ,

characterized

in that retaining means ( 24 ) are provided for holding the holding unit ( 19 ), in that the retention means ( 24 ) have a first retaining part ( 32 ) with the holding unit ( 19 ) held thereon and a second retaining part ( 31 ) with a magnetic bearing ( 33 , 35 ) acting between the first retaining part ( 32 ) and the second retaining part ( 31 ), and wherein the adjustment means ( 13 , 25 , 26 ) acts on the first retaining part ( 32 ) in the working position in order to adjust the holding unit ( 19 ), to move with respect to the second retaining part ( 31 ) by means of the magnetic bearing ( 33 , 35 ), the first retaining part ( 32 ) together with the holding unit ( 19 ) that is held by it.

7. The collecting apparatus as claimed in claim 6 ,

characterized

in that a sliding layer ( 54 ) is provided between the first retaining part ( 32 ) and the second retaining part ( 31 ).

8. The collecting apparatus as claimed in claim 6 ,

characterized

in that a projection ( 41 ) is provided on the lower face of the second retaining part ( 31 ), and projects into an elongated hole ( 42 ) which is formed in the first retaining part ( 32 ).

9. The collecting apparatus as claimed in claim 6 ,

characterized

in that the control means ( 7 , 50 ) drive the adjustment means ( 13 , 25 , 26 ) as a function of any movement applied by the user, as detected by the input means ( 51 ), such that the first retaining part ( 32 ), together with the holding unit ( 19 ) held by it, is shifted with respect to the second retaining part ( 31 ) in a corresponding manner to the movement applied by the user.

10. The collecting apparatus as claimed in claim 4 ,

characterized

in that the holding unit ( 19 ) is designed to hold a large number of collecting means ( 21 ), and

in that identification means ( 16 ) are provided, in order to identify the position of the individual collecting means ( 21 ) in the working position.

11. The collecting apparatus as claimed in claim 10 ,

characterized

in that the holding unit ( 19 ) has at least one marking ( 22 , 23 ), and in that the identification means ( 16 ) are designed such that, by monitoring the marking ( 22 , 23 ), they deduce the position of the individual collecting means ( 21 ) in the working position.

12. The collecting apparatus as claimed in claim 1 ,

characterized

in that the holding unit ( 19 ) is held by retaining means ( 24 ) and can be removed from the retention means ( 24 ).

13. The collecting apparatus as claimed in claim 1 ,

characterized

in that the holding unit ( 19 ) is designed to hold a large number of collecting means ( 21 ).

14. The collecting apparatus as claimed in claim 1 ,

characterized

in that input means ( 51 ) are provided for detecting any movement applied by a user, and in that the control means ( 7 , 50 ) are designed such that they convert any movement applied by a user, as detected by the input means ( 51 ), to corresponding adjustment signals for the adjustment means ( 13 , 25 , 26 ), in order to move the holding unit ( 19 ) in a corresponding manner to the movement applied by the user.

15. The collecting apparatus as claimed in claim 1 ,

characterized

in that the holding unit ( 19 ) is designed to hold a large number of collecting means ( 21 ), and

in that the control means ( 7 ) are designed such that, by producing appropriate adjustment signals for the adjustment means ( 13 ), they position a specific collecting means ( 21 ) in order to collect an object which is released from the mass.

16. The collecting apparatus as claimed in claim 1 ,

characterized

in that the holding unit ( 19 ) is designed to hold a large number of collecting means ( 21 ), in that a number of objects which can be released from the mass are defined, and in that the control means ( 7 ) are designed such that, by producing appropriate adjustment signals for the adjustment means ( 31 ), they automatically adjust the holding unit ( 19 ) such that different collecting means ( 21 ) are positioned successively in order to collect a respectively predefined object which is released from the mass.

17. The collecting apparatus as claimed in claim 1 ,

characterized

in that the holding unit ( 19 ) is designed to hold a large number of collecting means ( 21 ),

in which case the collecting means ( 21 ) can be fitted to the holding unit ( 19 ) distributed in the circumferential direction, and

in that the second adjustment device has a rotary drive ( 15 ) for rotating the holding unit ( 19 ) essentially parallel to the plane of the mount ( 3 ) which has the mass.

18. The collecting apparatus as claimed in claim 1 ,

characterized

in that the second adjustment device has an adjustment mechanism ( 17 ) with an adjustment pin ( 18 ), which, firstly, is used as a stop in the working position and, secondly, appropriately adjusts the holding unit ( 19 ) in the working position when the adjustment pin ( 18 ) is moved.

19. Collecting apparatus for collecting objects which are released, in particular by means of laser irradiation, from a mass which is located on a mount ( 3 ),

having a holding unit ( 19 ) for holding at least one collecting means ( 21 ) for collecting an object which is released from the mass, and

having adjustment means ( 13 ) for adjusting the holding unit ( 19 ) in order in this way to position the holding unit ( 19 ),

characterized

in that control means ( 7 , 50 ) are provided for automatic production of adjustment signals for the adjustment means ( 13 ),

in that the adjustment means ( 13 ) are designed such that they automatically adjust the holding unit ( 19 ) in accordance with the adjustment signals from the control means ( 7 , 50 ), and

in that the adjustment means ( 13 , 17 ) are designed such that, in the working position, they allow automatic adjustment of the holding unit ( 19 ) essentially parallel to the plane of the mount ( 3 ) in order to view, using a microscope, the object collected by the collecting means ( 21 ).

20. The collecting apparatus as claimed in claim 19 ,

characterized

in that a null position is defined for the collecting means ( 21 ) in the working position, and

in that the control means ( 7 , 50 ) are designed such that, after adjustment of the holding unit ( 19 ) together with the collecting means ( 21 ) held by it, from the null position, by means of appropriate actuation of the adjustment means ( 13 , 17 ), said control means (7, 50 ) automatically reset to the null position the holding unit ( 19 ) together with the collecting means ( 21 ) held by it.

21. The collecting apparatus as claimed in claim 19 ,

characterized

in that retaining means ( 24 ) are provided for holding the holding unit ( 19 ),

in that the retention means ( 24 ) have a first retaining part ( 32 ) with the holding unit ( 19 ) held thereon and a second retaining part ( 31 ) with a magnetic bearing ( 33 , 35 ) acting between the first retaining part ( 32 ) and the second retaining part ( 31 ), and

wherein the adjustment means ( 13 , 25 , 26 ) acts on the first retaining part ( 32 ) in the working position in order to adjust the holding unit ( 19 ), to move with respect to the second retaining part ( 31 ) by means of the magnetic bearing ( 33 , 35 ), the first retaining part ( 32 ) together with the holding unit ( 19 ) that is held by it.

22. The collecting apparatus as claimed in claim 19 ,

characterized

in that the holding unit ( 19 ) is designed to hold a large number of collecting means ( 21 ), and

in that identification means ( 16 ) are provided, in order to identify the position of the individual collecting means ( 21 ) in the working position.

23. Collecting apparatus for collecting objects which are released, in particular by means of laser irradiation, from a mass which is located on a mount ( 3 ),

having a holding unit ( 19 ) for holding at least one collecting means ( 21 ) for collecting an object which is released from the mass, and

having adjustment means ( 13 ) for adjusting the holding unit ( 19 ) in order in this way to position the holding unit ( 19 ),

characterized

in that control means ( 7 , 50 ) are provided for automatic production of adjustment signals for the adjustment means ( 13 ),

in that the adjustment means ( 13 ) are designed such that they automatically adjust the holding unit ( 19 ) in accordance with the adjustment signals from the control means ( 7 , 50 ), and

in that the holding unit ( 19 ) is held by retaining means ( 24 ) and can be removed from the retaining means ( 24 ).

24. The collecting apparatus as claimed in claim 23 ,

characterized

in that retaining means ( 24 ) are provided for holding the holding unit ( 19 ),

in that the retention means ( 24 ) have a first retaining part ( 32 ) with the holding unit ( 19 ) held thereon and a second retaining part ( 31 ), and

wherein the adjustment means ( 13 , 25 , 26 ) acts on the first retaining part ( 32 ) in the working position in order to adjust the holding unit ( 19 ), to move with respect to the second retaining part ( 31 ), the first retaining part ( 32 ) together with the holding unit ( 19 ) that is held by it.

25. Collecting apparatus for collecting objects which are released, in particular by means of laser irradiation, from a mass which is located on a mount ( 3 ),

having a holding unit ( 19 ) for holding at least one collecting means ( 21 ) for collecting an object which is released from the mass, and

having adjustment means ( 13 ) for adjusting the holding unit ( 19 ) in order in this way to position the holding unit ( 19 ),

characterized

in that control means ( 7 , 50 ) are provided for automatic production of adjustment signals for the adjustment means ( 13 ),

in that the adjustment means ( 13 ) are designed such that they automatically adjust the holding unit ( 19 ) in accordance with the adjustment signals from the control means ( 7 , 50 ), and

in that the holding unit ( 19 ) is designed to hold a large number of collecting means ( 21 ).

26. The collecting apparatus as claimed in claim 25 ,

characterized

in that the control means ( 7 ) are designed such that, by producing appropriate adjustment signals for the adjustment means ( 13 ), they position a specific collecting means ( 21 ) in order to collect an object which is released from the mass.

27. The collecting apparatus as claimed in claim 25 ,

characterized

in that the holding unit ( 19 ) is designed to hold a large number of collecting means ( 21 ),

in that a number of objects which can be released from the mass are defined, and

in that the control means ( 7 ) are designed such that, by producing appropriate adjustment signals for the adjustment means ( 31 ), they automatically adjust the holding unit ( 19 ) such that different collecting means ( 21 ) are positioned successively in order to collect a respectively predefined object which is released from the mass.

28. The collecting apparatus as claimed in claim 25 ,

characterized

in that the holding unit ( 19 ) is designed to hold a large number of collecting means ( 21 ), and

in that identification means ( 16 ) are provided, in order to identify the position of the individual collecting means ( 21 ) in the working position.

29. The collecting apparatus as claimed in claim 28 ,

characterized

in that the holding unit ( 19 ) has at least one marking ( 22 , 23 ), and

in that the identification means ( 16 ) are designed such that, by monitoring the marking ( 22 , 23 ), they deduce the position of the individual collecting means ( 21 ) in the working position.

30. Collecting apparatus for collecting objects which are released, in particular by means of laser irradiation, from a mass which is located on a mount ( 3 ),

having a holding unit ( 19 ) for holding at least one collecting means ( 21 ) for collecting an object which is released from the mass, and

having adjustment means ( 13 ) for adjusting the holding unit ( 19 ) in order in this way to position the holding unit ( 19 ),

characterized

in that control means ( 7 , 50 ) are provided for automatic production of adjustment signals for the adjustment means ( 13 ),

in that the adjustment means ( 13 ) are designed such that they automatically adjust the holding unit ( 19 ) in accordance with the adjustment signals from the control means ( 7 , 50 ),

in that input means ( 51 ) are provided for detecting any movement applied by a user, and

in that the control means ( 7 , 50 ) are designed such that they convert any movement applied by a user, as detected by the input means ( 51 ), to corresponding adjustment signals for the adjustment means ( 13 , 25 , 26 ), in order to move the holding unit ( 19 ) in a corresponding manner to the movement applied by the user.

31. The collecting apparatus as claimed in claim 30 ,

characterized

in that retaining means ( 24 ) are provided for holding the holding unit ( 19 ),

in that the retention means ( 24 ) have a first retaining part ( 32 ) with the holding unit ( 19 ) held thereon and a second retaining part ( 31 ), and

wherein the adjustment means ( 13 , 25 , 26 ) acts on the first retaining part ( 32 ) in the working position in order to adjust the holding unit ( 19 ), to move with respect to the second retaining part ( 31 ), the first retaining part ( 32 ) together with the holding unit ( 19 ) that is held by it, and

in that the control means ( 7 , 50 ) drive the adjustment means ( 13 , 25 , 26 ) as a function of any movement applied by the user, as detected by the input means ( 51 ), such that the first retaining part ( 32 ), together with the holding unit ( 19 ) held by it, is shifted with respect to the second retaining part ( 31 ) in a corresponding manner to the movement applied by the user.

Assignments (2)
CHANGE OF NAME Recorded Jun 6, 2013
From: CARL ZEISS MICROIMAGING GMBH
To: CARL ZEISS MICROSCOPY GMBH
Reel/Frame 030554/0419 →
MERGER Recorded May 5, 2010
From: P.A.L.M. MICROLASER TECHNOLOGIES GMBH
To: CARL ZEISS MICROIMAGING GMBH
Reel/Frame 024329/0971 →